FORENSIC SCIENCE- BIOLOGY- PAGE 2
FORENSIC SCIENCE- BIOLOGY- PAGE 2 MCQs
1. A growing research area, in DNA analysis using epigenetic alterations, focus on
(A) Differentially modified regions (B) Differentially methylated regions
(C) Differentially methylated RNAs (D) Differentially modified RNAs
Ans: B
2. The descending order of immunoglobulin concentration in human sera
(A) IgG, IgA, IgM, IgD and IgE
(B) IgA, IgM, IgG, IgD and IgE
(C) IgM, IgG, IgA, IgD and IgE
(D) IgG, IgM, IgA, IgD, and IgE
Ans: A
3. Polypeptides composed of D- aminoacids are not antigenic
(A) They are metabolised by tissue (B) They are not metabolised by tissue
(C) They are neutralised easily (D) Both (A) and (C)
Ans: B
4. T cell independent(TI) antigens
(A) Antibody response is limited to IgM and IgG3 (B) Do not show immunological memory
(C) Metabolized very slowly and remain in the body for a long time (D) All of the above
Ans: D
5. Antibody secreted into external secretions and guards mucosal surfaces
(A) IgE (B) IgG (C) IgA (D) Both (A) and (B)
Ans: C
6. C- reactive protein
(A) Reflects survival time after trauma (B) Reflects degree of tissue damage
(C) Are stable for one month (D) All of the above
Ans: D
7. Which of the following protein has applications in Forensic Neuropathology?
(A) S90 proteins (B) S100 proteins (C) S121 proteins (D) S200 proteins
Ans: B
8. The advantage of isoenzyme method
(A) Stable in stains for over four weeks (B) isoenzyme pattern differ in human and animal
(C) Distinct from vaginal secretions band patterns (D) All of the above
Ans: D
9. CD8+ T lymphocyte are involved in antigen presentations in
(A) MHC Class 1 pathway (B) MHC Class 2 pathway (C) MHC Class 3 pathway (D) Both (A) and (B)
Ans: A
10. HLA typing is used
(A) To assess compatibility before tissue transplantation (B) In disputed paternity (C) In finger printing (D) Both (A) and (B)
Ans: D
11. The forensic science is,
(A) The application of the technology and scientific knowledge for the analysis of crime scene evidence.
(B) Proper scientific techniques to understand a crime scene.
(C) The process in which a crime was committed.
(D) The science studying the origins and background of crime scene investigation.
Ans: A
12. Type II restriction endonucleases bind and cut DNA molecules at
(A) Palindromic sequences (B) AT rich sequences (C) GC rich sequences are (D) CpG Islands
Ans: A
13. The following is an example of an individual characteristic that can be associated with one individual?
(A) Custom paint on a vehicle (B) Fingerprint ridges (C) Blood types (D) Materials in plastic bags
Ans: B
14. The anthropometry is,
(A) The scientific study of the measurements and proportions of the human body.
(B) The scientific study of proportions of the human body.
(C) The study of the human health.
(D) None of above
Ans: A
15. Plasmids that have no apparent functional coding genes are called
(A) Archeaic plasmids (B) Crypitc plasmids (C) F plasmids (D) Degradative plasmid
Ans: B
16. Which cellular eukaryotic RNA fraction can be separated by passing through a column packed with cellulose beads bound to short chains of thymidine residues
(A) t-RNA (B) r- RNA (C) hn- RNA (D) m-RNA
Ans: D
17. The study of fingerprints as a method of personal identification was done by,
(A) Neil Armstrong (B) Shankeran (C) Lattes (D) Galton
Ans: D
18. The blood group determining technique by using the dried blood stain was developed by,
(A) Gross (B) Locard (C) Bertillon (D) Lattes
Ans: D
19. For generating a cDNA library the m -RNA is converted to double stranded DNA which is accomplished by using
(A) Restriction endonuclease
(B) Reverse transcriptase
(C) Reverse transcriptase & Klenow fragment
(D) Restriction endonuclease & Klenow fragment
Ans: C
20. Extra or additional nuclear genetic material is found in
(A) Mitochondria (B) Mitochondria and plastids both (C) Nucleus (D) Plastid and nucleus
Ans: B
21. Finger prints in Indian population mainly categorize into
(A) Whorl (B) Circle (C) Loop (D) Arch
Ans: C
22. LCN profiles are generally
(A) Reproducible (B) Not reproducible (C) Conclusive in forensic case (D) Both (A) and (C)
Ans: B
23. SNPs account for ……….. of all differences between unrelated persons
(A) More than 95% (B) More than 90% (C) More than 85% (D) More than 80%
Ans: B
24. A peptide bond
(A) is rigid and planar. (B) The atoms in it are Cα-C-N-Cα. (C) is coplanar (D) All of the above
Ans: D
25. SNP genotyping generally use which of the following allele discrimination method(s)
(A) Hybridization/annealing (B) Primer extension (C) Enzyme cleavage (D) All of the above
Ans: D
26. Pyrosequencing, sequences short stretches of DNA, detects
(A) Pyro primers (B) Pyrosulphates (C) Poly adenosine (D) Pyrophosphate
Ans: D
27. Y-STR typing is utmost importance for analyzing
(A) Multiple DNA samples (B) Contaminated DNA samples
(C) Mixture of male and female DNA samples (D) Only fresh DNA samples
Ans: C
28. CODIS stands for
(A) Combined DNA Information System (B) Combined DNA Information Site
(C) Combined DNA Information Source (D) Combined DNA Index System
Ans: D
29. Analysing bacterial soil sample for murder evidences,the DNA marker is
(A) 16S DNA profiling (B) 5S DNA profiling (C) RAPDs (D) 23S DNA profiling
Ans: A
30. Dogs hair used for forensic investigation relies on
(A) STRs (B) VNTRs (C) RAPDs (D) AFLPs
Ans: A
31. In the complement cascade, the core event is the activation of
(A) C3 (B) C42 (C) C4 (D) C36
Ans: A
32. For any serological test generally, sensitivity and specificity are
(A) In direct proportion (B) In inverse proportion (C) Dependent on cell types (D) Independent of cell type
Ans: B
33. Finger printing contaminants and evaluating the concentration of these compounds is the focus in
(A) DNA finger printing (B) Forensic Medicine (C) Environmental Forensic (D) Both (A) and (B)
Ans: C
34. 2D gas chromatography, a powerful tool for complex mixture separation and characterization is
(A) GCxFC (B) GCxMS (C) GCxLC (D) GCxGC
Ans: D
35. Which of the following is not a biomarker in chemical finger printing using GCMS?
(A) Volatile Organic Compounds (B) Steranes (C) Triterpenes (D) Diterpenes
Ans: A
36. An important technique to provide information regarding status of ground water contaminants
(A) IRMS (B) GCMS (C) 2D GC (D) GIRMS
Ans: D
37. Organic polymers such as plastic and polymers are identified using
(A) PMC (B) FTIR (C) PLM (D) Both (B) and (C)
Ans: B
38. The leaded particles classified as autoexhaust
(A) Pb-Zn (B) Pb-Br (C) Pb-Cr (D) Pb only
Ans: B
39. Which of the following is a key identifier for common indoors and out door dust particle
(A) Lb-Br (B) Skin cells and mucous (C) Fungal cells (D) Skin cells
Ans: D
40. Petroleum coke in unknown sample can be identified by the presence of
(A) Sulfur (B) Nickel (C) Lead (D) Both (A) and (B)
Ans: A
41. Forensic epidemiology helps to resolve issues related to
(A) Murder (B) Bioterrorism (C) Chemical warfare (D) Both (B) and (C)
Ans: B
42. The first massive DNA sequencing method commercialized, used
(A) E.coil cloning technique (B) Pyro sequencing technique
(C) Cryptic cloning technique (D) Yeast cloning technique
Ans: B
43. Sequencing of H.influenzae introduced a new method for sequencing cellular genome
(A) Whole genome shot gun method (B) RFLPs (C) VNTRs (D) RAPDs
Ans: A
44. The marker used, in most commercially available kits, for DNA sex determinations in Forensics
(A) Troponin gene (B) Amelogenin gene (C) α globulin gene (D) Actin gene
Ans: B
45. Which of the following, externally visible characteristic, be predicted and used in crime detection, based on DNA evidence
(A) Black hair colour (B) Red hair colour (C) Blue iris colour (D) Both (B) and (C)
Ans: D
46. DNA methylations can be influenced by
(A) Diet (B) Age (C) Life style choice (D) All of the above
Ans: D
47. Indiviuals with red hair express an increase in
(A) Eumelanin (B) Pheomelanin (C) Gamma melanin (D) Acromelanin
Ans: B
48. A global prediction model for skin colour, commercially used is based on
(A) 36 markers distributed among16 pigmentation gene (B) 25 markers distributed among 15 pigmentation gene
(C) 20 markers distributed among 5 pigmentation gene (D) 10 markers distributed among 5 pigmentation gene
Ans: A
49. Common cell types recovered from scenes of crime used for DNA phenotyping
(A) RBC (B) WBC (C) Epithelial cells (D) Both (B) and (C)
Ans: D
50. VNTR and other loci are used in Forensic analysis, as they are considered to be
(A) Expressing Hardy –Weinberg equilibrium (B) Accessible Allele frequency data base
(C) Selectively neutral or nearly so (D) Both (A) and (B)
Ans: C
(A) Differentially modified regions (B) Differentially methylated regions
(C) Differentially methylated RNAs (D) Differentially modified RNAs
Ans: B
2. The descending order of immunoglobulin concentration in human sera
(A) IgG, IgA, IgM, IgD and IgE
(B) IgA, IgM, IgG, IgD and IgE
(C) IgM, IgG, IgA, IgD and IgE
(D) IgG, IgM, IgA, IgD, and IgE
Ans: A
3. Polypeptides composed of D- aminoacids are not antigenic
(A) They are metabolised by tissue (B) They are not metabolised by tissue
(C) They are neutralised easily (D) Both (A) and (C)
Ans: B
4. T cell independent(TI) antigens
(A) Antibody response is limited to IgM and IgG3 (B) Do not show immunological memory
(C) Metabolized very slowly and remain in the body for a long time (D) All of the above
Ans: D
5. Antibody secreted into external secretions and guards mucosal surfaces
(A) IgE (B) IgG (C) IgA (D) Both (A) and (B)
Ans: C
6. C- reactive protein
(A) Reflects survival time after trauma (B) Reflects degree of tissue damage
(C) Are stable for one month (D) All of the above
Ans: D
7. Which of the following protein has applications in Forensic Neuropathology?
(A) S90 proteins (B) S100 proteins (C) S121 proteins (D) S200 proteins
Ans: B
8. The advantage of isoenzyme method
(A) Stable in stains for over four weeks (B) isoenzyme pattern differ in human and animal
(C) Distinct from vaginal secretions band patterns (D) All of the above
Ans: D
9. CD8+ T lymphocyte are involved in antigen presentations in
(A) MHC Class 1 pathway (B) MHC Class 2 pathway (C) MHC Class 3 pathway (D) Both (A) and (B)
Ans: A
10. HLA typing is used
(A) To assess compatibility before tissue transplantation (B) In disputed paternity (C) In finger printing (D) Both (A) and (B)
Ans: D
11. The forensic science is,
(A) The application of the technology and scientific knowledge for the analysis of crime scene evidence.
(B) Proper scientific techniques to understand a crime scene.
(C) The process in which a crime was committed.
(D) The science studying the origins and background of crime scene investigation.
Ans: A
12. Type II restriction endonucleases bind and cut DNA molecules at
(A) Palindromic sequences (B) AT rich sequences (C) GC rich sequences are (D) CpG Islands
Ans: A
13. The following is an example of an individual characteristic that can be associated with one individual?
(A) Custom paint on a vehicle (B) Fingerprint ridges (C) Blood types (D) Materials in plastic bags
Ans: B
14. The anthropometry is,
(A) The scientific study of the measurements and proportions of the human body.
(B) The scientific study of proportions of the human body.
(C) The study of the human health.
(D) None of above
Ans: A
15. Plasmids that have no apparent functional coding genes are called
(A) Archeaic plasmids (B) Crypitc plasmids (C) F plasmids (D) Degradative plasmid
Ans: B
16. Which cellular eukaryotic RNA fraction can be separated by passing through a column packed with cellulose beads bound to short chains of thymidine residues
(A) t-RNA (B) r- RNA (C) hn- RNA (D) m-RNA
Ans: D
17. The study of fingerprints as a method of personal identification was done by,
(A) Neil Armstrong (B) Shankeran (C) Lattes (D) Galton
Ans: D
18. The blood group determining technique by using the dried blood stain was developed by,
(A) Gross (B) Locard (C) Bertillon (D) Lattes
Ans: D
19. For generating a cDNA library the m -RNA is converted to double stranded DNA which is accomplished by using
(A) Restriction endonuclease
(B) Reverse transcriptase
(C) Reverse transcriptase & Klenow fragment
(D) Restriction endonuclease & Klenow fragment
Ans: C
20. Extra or additional nuclear genetic material is found in
(A) Mitochondria (B) Mitochondria and plastids both (C) Nucleus (D) Plastid and nucleus
Ans: B
21. Finger prints in Indian population mainly categorize into
(A) Whorl (B) Circle (C) Loop (D) Arch
Ans: C
22. LCN profiles are generally
(A) Reproducible (B) Not reproducible (C) Conclusive in forensic case (D) Both (A) and (C)
Ans: B
23. SNPs account for ……….. of all differences between unrelated persons
(A) More than 95% (B) More than 90% (C) More than 85% (D) More than 80%
Ans: B
24. A peptide bond
(A) is rigid and planar. (B) The atoms in it are Cα-C-N-Cα. (C) is coplanar (D) All of the above
Ans: D
25. SNP genotyping generally use which of the following allele discrimination method(s)
(A) Hybridization/annealing (B) Primer extension (C) Enzyme cleavage (D) All of the above
Ans: D
26. Pyrosequencing, sequences short stretches of DNA, detects
(A) Pyro primers (B) Pyrosulphates (C) Poly adenosine (D) Pyrophosphate
Ans: D
27. Y-STR typing is utmost importance for analyzing
(A) Multiple DNA samples (B) Contaminated DNA samples
(C) Mixture of male and female DNA samples (D) Only fresh DNA samples
Ans: C
28. CODIS stands for
(A) Combined DNA Information System (B) Combined DNA Information Site
(C) Combined DNA Information Source (D) Combined DNA Index System
Ans: D
29. Analysing bacterial soil sample for murder evidences,the DNA marker is
(A) 16S DNA profiling (B) 5S DNA profiling (C) RAPDs (D) 23S DNA profiling
Ans: A
30. Dogs hair used for forensic investigation relies on
(A) STRs (B) VNTRs (C) RAPDs (D) AFLPs
Ans: A
31. In the complement cascade, the core event is the activation of
(A) C3 (B) C42 (C) C4 (D) C36
Ans: A
32. For any serological test generally, sensitivity and specificity are
(A) In direct proportion (B) In inverse proportion (C) Dependent on cell types (D) Independent of cell type
Ans: B
33. Finger printing contaminants and evaluating the concentration of these compounds is the focus in
(A) DNA finger printing (B) Forensic Medicine (C) Environmental Forensic (D) Both (A) and (B)
Ans: C
34. 2D gas chromatography, a powerful tool for complex mixture separation and characterization is
(A) GCxFC (B) GCxMS (C) GCxLC (D) GCxGC
Ans: D
35. Which of the following is not a biomarker in chemical finger printing using GCMS?
(A) Volatile Organic Compounds (B) Steranes (C) Triterpenes (D) Diterpenes
Ans: A
36. An important technique to provide information regarding status of ground water contaminants
(A) IRMS (B) GCMS (C) 2D GC (D) GIRMS
Ans: D
37. Organic polymers such as plastic and polymers are identified using
(A) PMC (B) FTIR (C) PLM (D) Both (B) and (C)
Ans: B
38. The leaded particles classified as autoexhaust
(A) Pb-Zn (B) Pb-Br (C) Pb-Cr (D) Pb only
Ans: B
39. Which of the following is a key identifier for common indoors and out door dust particle
(A) Lb-Br (B) Skin cells and mucous (C) Fungal cells (D) Skin cells
Ans: D
40. Petroleum coke in unknown sample can be identified by the presence of
(A) Sulfur (B) Nickel (C) Lead (D) Both (A) and (B)
Ans: A
41. Forensic epidemiology helps to resolve issues related to
(A) Murder (B) Bioterrorism (C) Chemical warfare (D) Both (B) and (C)
Ans: B
42. The first massive DNA sequencing method commercialized, used
(A) E.coil cloning technique (B) Pyro sequencing technique
(C) Cryptic cloning technique (D) Yeast cloning technique
Ans: B
43. Sequencing of H.influenzae introduced a new method for sequencing cellular genome
(A) Whole genome shot gun method (B) RFLPs (C) VNTRs (D) RAPDs
Ans: A
44. The marker used, in most commercially available kits, for DNA sex determinations in Forensics
(A) Troponin gene (B) Amelogenin gene (C) α globulin gene (D) Actin gene
Ans: B
45. Which of the following, externally visible characteristic, be predicted and used in crime detection, based on DNA evidence
(A) Black hair colour (B) Red hair colour (C) Blue iris colour (D) Both (B) and (C)
Ans: D
46. DNA methylations can be influenced by
(A) Diet (B) Age (C) Life style choice (D) All of the above
Ans: D
47. Indiviuals with red hair express an increase in
(A) Eumelanin (B) Pheomelanin (C) Gamma melanin (D) Acromelanin
Ans: B
48. A global prediction model for skin colour, commercially used is based on
(A) 36 markers distributed among16 pigmentation gene (B) 25 markers distributed among 15 pigmentation gene
(C) 20 markers distributed among 5 pigmentation gene (D) 10 markers distributed among 5 pigmentation gene
Ans: A
49. Common cell types recovered from scenes of crime used for DNA phenotyping
(A) RBC (B) WBC (C) Epithelial cells (D) Both (B) and (C)
Ans: D
50. VNTR and other loci are used in Forensic analysis, as they are considered to be
(A) Expressing Hardy –Weinberg equilibrium (B) Accessible Allele frequency data base
(C) Selectively neutral or nearly so (D) Both (A) and (B)
Ans: C
51. The plasma membrane of a human cell isTop of FormBottom of Form
(A) a single layered cell membrane (B) a double layer of phospholipids
(C) a membrane that contains pili on its cell surface (D) a double layer of carbohydrate enclosing the cell
Ans: B
52. Cosmid pLFR -5 has
(A) 2 COS site and Sca I restriction endonuclease site (B) Multiple cloning sequences
(C) An origin of DNA replication & Tetracycline resistance gene (D) All of the above
Ans: D
53. Which features of DNA prevents it from passing through the cell membrane of bacteria
(A) Hydrophobic (B) Hydrophilic (C) Non polar (D) Acidic
Ans: B
54. Plasma membrane proteins on a cell will transport
(A) molecules through the cell membrane (B) oxygen into the cell (C) carbon dioxide into the cell (D) All of the above
Ans: D
55. Engineered wood products may be preferred over solid wood in some applications due to,
(A) It is man-made; it can be designed to meet application-specific performance requirements.
(B) Available in a wide variety of thicknesses, sizes, grades
(C) It can be produced from relatively small trees, rather than the large tree.
(D) All of the above
Ans: D
56. In E.coli a short sequences in the mRNA transcript that control the correct translation
(A) Shine Dalgarno sequence (B) Ribosome binding site (C) A Site (D) Both (A) and (B)
Ans: D
57. Fusion proteins can be purified by
(A) Immuno affinity chromatography (B) Density gradient (C) Electrophoresis (D) Both (B) and (C)
Ans: A
58. Birch is a type of,
(A) Timber (B) Paper (C) Cloth material (D) None of the above
Ans: A
59. Best expression vectors have
(A) Strong promoters (B) Constitutive promoters (C) Regulatable strong promoters (D) Both (A) and (B)
Ans: C
60. The characteristic of the cell membrane
(A) It has many proteins embedded in it. (B) It regulates the entry and exit of the cell.
(C) Many molecules cross the cell membrane by diffusion and osmosis. (D) All of the above
Ans: D
61. In the yeast expression system human Cu/Zn-SOD c DNA has,
(A) Direct expression (B) Constitutive expression (C) Regulated expression (D) Both (A) and (B)
Ans: D
62. The Human Papova BK virus can be structured as
(A) Shuttle vector (B) YAC (C) Transport vector (D) Regulated Vector
Ans: A
63. Commercial production of amino acids as fermentation products uses,
(A) Cornebacterium spp (B) Brevi bacterium spp (C) .E.coli (D) Both (A) and (B)
Ans: D
64. The movement of fluid between compartments is regulated by
(A) Glomerular filtration rate (B) Parathyroid hormone (C) Osmoticand hydrostatic pressures (D) ATP
Ans: C
65. For a successful Ti plasmid – derived vector system which gene(s) need to be removed
(A) Auxin genes (B) Cytokinin gene (C) Opine –synthesis gene (D) All of the above
Ans: D
66. Which of the following is strongly recommended reporter gene in transgenic food crops?
(A) Neomycin phosphotransferase (B) D glucoronidase
(C) Gentamycin acetyl tranferease (D) Chloramphenicol acetyltransferase
Ans: B
67. The house of genetic Material is its,
(A) Nucleus (B) Mitochondria (C) Nucleolus (D) Golgi body
Ans: A
68. At a wound site type of proteins that escort cells to move to their destination is,
(A) Gap junctions (B) Cell adhesion molecules (C) Tight junctions (D) Desmosomes
Ans: B
69. The important function of Nucleolus is to,
(A) Synthesize protein (B) Synthesize ribosome
(C) Synthesize ribosome and protein both (D) Synthesize of microtubules
Ans: C
70. As stated in “Regulations and Guidelines on Biosafety of Recombinant DNA Research and Bio contaminants 2017” the role of Institutional Biosafety Committee is
(A) Advisory /Regulatory (B) Regulatory/Approval
(C) Advisory/Approval (D) Monitoring/Approval
Ans: B
71. The mediator of hypersensitivity Type I reaction
(A) IgM (B) IgA (C) Histamine (D) IgG
Ans: C
72. “Protective biological lubricants” are
(A) membrane bound glycogens (B) membrane bound glycoproteins (C) membrane bound srarch (D) membrane bound chitins
Ans: B
73. The fatty acid tails of the phospholipid molecule in the cell membrane is
(A) Ahydrophobic (B) Hydrophilic (C) Amphipathic (D) Neutral
Ans: A
74. The proteins that are employed in mtDNA repair are encoded by,
(A) nuclear genes (B) hydrolase enzymes (C) lipolytic enzymes (D) epimerase enzymes
Ans: A
75. The assimilation of liquid into a cell by the budding of small vesicles from the cell membrane.
(A) Pinocytosis (B) Phagocytosis (C) Exocytosis (D) Digestion
Ans: A
76. White blood cells and embryonic cells exhibits ———locomotion in human body,
(A) Amoeboid locomotion (B) Gliding locomotion (C) Swarming locomotion (D) Flagellar locomotion
Ans: A
77. Transformation of cells broadly refers as,
(A) the change in phenotype of a cell due to a new genetic material. (B) no contact inhibition
(C) the change in phenotype of a cell due to a new biochemical material. (D) when cells are non-anchorage dependent
Ans: A
78. Delayed hypersensitivity is induced by
(A) Circulating antibodies (B) Sensitized T cells
(C) Sensitized B cells (D) Both (A) and (C)
Ans: B
79. Lectins are potential tools for
(A) Isolation of glycoproteins (B) Identification and separation of cell types
(C) Identification of cell surface receptors (D) All of the above
Ans: D
80. Which of the following feature(s) renders Lectin its application in Forensic Science
(A) Proteinaceous (B) Sensitivity (C) Agglutination (D) Both (A) and (B)
Ans: C
81. All amino acids, except ———— are optically active.
(A) Glycine (B) Alanine (C) Tryptophan (D) All of the above
Ans: A
82. There are no introns in
(A) Animal mt DNA (B) Yeast mt DNA (C) ct DNA in the chloroplast (D) ct DNA of Angiosperms
Ans: A
83. Shine Dalgarno sequences is
(A) Polypurine rich stretch (B) Complementary to a highly conserved sequences of 16S rRNA
(C) Polypyramidine rich stretch (D) Both (A) & (B)
Ans: D
84. Most prokaryotes have a
(A) peptidoglycan cell wall (B) Nucleus (C) Mitochondria (D) Golgi body
Ans: A
85. ‘Knick’ in the polypeptide chain is because of,
(A) Tyrosine (B) Proline (C) Leucine (D) Tryptophan
Ans: B
86. Peptidyl tranferase activity is expressed by
(A) 16S r RNA (B) 18S r RNA (C) 5 S r RNA (D) 23 S r RNA
Ans: D
87. Domains are the units of polypeptides with characteristics of,
(A) Primary lipid that is structurally independent of the other domains in the polypeptide Chain
(B) smallcompact globular protein that is structurally independent of the other Domains in the polypeptide chain
(C) secondary protein that is structurally dependent on the other domains in the Polypeptide chain
(D) tertiary protein that is structurally dependent on the other domains in the polypeptide chain
Ans: B
88. Isoforms are those proteins which are encoded by different genes and perform the same function having,
(A) different tertiary structure (B) same primary structure
(C) different secondary structure (D) different primary structure
Ans: D
89. Cognate tRNAs are
(A) tRNAs accepting one amino acid (B) tRNAs recognized by same synthase
(C) multiple tRNAs representing the same amino acid (D) tRNAs accepting modified amino acids
Ans: B
90. Dactylograpy is
(A) Study of DNA profiling (B) Study of DNA finger printing
(C) Most specific and sensitive for identification (D) Both (B) and (C)
Ans: D
91. The semi conservative nature of DNA replication was confirmed experimentally by
(A) Watson and Crick-1953 (B) Watson and Crick-1958
(C) Meselson and Stahl-1953 (D) Meselson and Stahl-1958
Ans: D
92. The organelle functioning as a semi-autonomous organelle is,
(A) Nucleus (B) Nucleolus (C) Mitochondria (D) Golgi body
Ans: C
93. No longer useful organelles are digested by which organelle?
(A) Ribosomes (B) Lysosomes (C) Chromatin (D) Mitochondria
Ans: B
94. The non-membranous cell structure is,
(A) Chloroplast (B) Mitochondria (C) Ribosome (D) Nucleus
Ans: C
95. DNases cleave DNA target sites at
(A) Both strands of duplex DNA (B) One strand of duplex DNA (C) Terminal ends (D) Both (A) & (B)
Ans: D
96. Which of the following is a chemical nucleotide sequencing method?
(A) Edmans method (B) Sanger method (C) Automated sequencing method (D) Maxam-Gilbert method
Ans: D
97. The smallest virus STNV stands for
(A) Small tobacco necrosis virus (B) Satellite tobacco necrosis virus (C) Small tea necrosis virus (D) Satellite tea necrosis virus
Ans: B
98. Viroids have a signatory feature
(A) Infect plants only (B) Infect lower vertebrates only (C) Imperfectly base paired RNA (D) Imperfectly base paired DNA
Ans: C
99. Basically an RFLP in an SNP that is located in the target site of a
(A) Exonuclease (B) Restriction enzymes (C) Palindrom (D) Endonuclease
Ans: B
100. PCR is using sequencing methods for generating sequence are,
(A) Templates (B) Sanger’s method (C) Sanger’s method and LMPCR (D) None of Above
Ans: D
(A) a single layered cell membrane (B) a double layer of phospholipids
(C) a membrane that contains pili on its cell surface (D) a double layer of carbohydrate enclosing the cell
Ans: B
52. Cosmid pLFR -5 has
(A) 2 COS site and Sca I restriction endonuclease site (B) Multiple cloning sequences
(C) An origin of DNA replication & Tetracycline resistance gene (D) All of the above
Ans: D
53. Which features of DNA prevents it from passing through the cell membrane of bacteria
(A) Hydrophobic (B) Hydrophilic (C) Non polar (D) Acidic
Ans: B
54. Plasma membrane proteins on a cell will transport
(A) molecules through the cell membrane (B) oxygen into the cell (C) carbon dioxide into the cell (D) All of the above
Ans: D
55. Engineered wood products may be preferred over solid wood in some applications due to,
(A) It is man-made; it can be designed to meet application-specific performance requirements.
(B) Available in a wide variety of thicknesses, sizes, grades
(C) It can be produced from relatively small trees, rather than the large tree.
(D) All of the above
Ans: D
56. In E.coli a short sequences in the mRNA transcript that control the correct translation
(A) Shine Dalgarno sequence (B) Ribosome binding site (C) A Site (D) Both (A) and (B)
Ans: D
57. Fusion proteins can be purified by
(A) Immuno affinity chromatography (B) Density gradient (C) Electrophoresis (D) Both (B) and (C)
Ans: A
58. Birch is a type of,
(A) Timber (B) Paper (C) Cloth material (D) None of the above
Ans: A
59. Best expression vectors have
(A) Strong promoters (B) Constitutive promoters (C) Regulatable strong promoters (D) Both (A) and (B)
Ans: C
60. The characteristic of the cell membrane
(A) It has many proteins embedded in it. (B) It regulates the entry and exit of the cell.
(C) Many molecules cross the cell membrane by diffusion and osmosis. (D) All of the above
Ans: D
61. In the yeast expression system human Cu/Zn-SOD c DNA has,
(A) Direct expression (B) Constitutive expression (C) Regulated expression (D) Both (A) and (B)
Ans: D
62. The Human Papova BK virus can be structured as
(A) Shuttle vector (B) YAC (C) Transport vector (D) Regulated Vector
Ans: A
63. Commercial production of amino acids as fermentation products uses,
(A) Cornebacterium spp (B) Brevi bacterium spp (C) .E.coli (D) Both (A) and (B)
Ans: D
64. The movement of fluid between compartments is regulated by
(A) Glomerular filtration rate (B) Parathyroid hormone (C) Osmoticand hydrostatic pressures (D) ATP
Ans: C
65. For a successful Ti plasmid – derived vector system which gene(s) need to be removed
(A) Auxin genes (B) Cytokinin gene (C) Opine –synthesis gene (D) All of the above
Ans: D
66. Which of the following is strongly recommended reporter gene in transgenic food crops?
(A) Neomycin phosphotransferase (B) D glucoronidase
(C) Gentamycin acetyl tranferease (D) Chloramphenicol acetyltransferase
Ans: B
67. The house of genetic Material is its,
(A) Nucleus (B) Mitochondria (C) Nucleolus (D) Golgi body
Ans: A
68. At a wound site type of proteins that escort cells to move to their destination is,
(A) Gap junctions (B) Cell adhesion molecules (C) Tight junctions (D) Desmosomes
Ans: B
69. The important function of Nucleolus is to,
(A) Synthesize protein (B) Synthesize ribosome
(C) Synthesize ribosome and protein both (D) Synthesize of microtubules
Ans: C
70. As stated in “Regulations and Guidelines on Biosafety of Recombinant DNA Research and Bio contaminants 2017” the role of Institutional Biosafety Committee is
(A) Advisory /Regulatory (B) Regulatory/Approval
(C) Advisory/Approval (D) Monitoring/Approval
Ans: B
71. The mediator of hypersensitivity Type I reaction
(A) IgM (B) IgA (C) Histamine (D) IgG
Ans: C
72. “Protective biological lubricants” are
(A) membrane bound glycogens (B) membrane bound glycoproteins (C) membrane bound srarch (D) membrane bound chitins
Ans: B
73. The fatty acid tails of the phospholipid molecule in the cell membrane is
(A) Ahydrophobic (B) Hydrophilic (C) Amphipathic (D) Neutral
Ans: A
74. The proteins that are employed in mtDNA repair are encoded by,
(A) nuclear genes (B) hydrolase enzymes (C) lipolytic enzymes (D) epimerase enzymes
Ans: A
75. The assimilation of liquid into a cell by the budding of small vesicles from the cell membrane.
(A) Pinocytosis (B) Phagocytosis (C) Exocytosis (D) Digestion
Ans: A
76. White blood cells and embryonic cells exhibits ———locomotion in human body,
(A) Amoeboid locomotion (B) Gliding locomotion (C) Swarming locomotion (D) Flagellar locomotion
Ans: A
77. Transformation of cells broadly refers as,
(A) the change in phenotype of a cell due to a new genetic material. (B) no contact inhibition
(C) the change in phenotype of a cell due to a new biochemical material. (D) when cells are non-anchorage dependent
Ans: A
78. Delayed hypersensitivity is induced by
(A) Circulating antibodies (B) Sensitized T cells
(C) Sensitized B cells (D) Both (A) and (C)
Ans: B
79. Lectins are potential tools for
(A) Isolation of glycoproteins (B) Identification and separation of cell types
(C) Identification of cell surface receptors (D) All of the above
Ans: D
80. Which of the following feature(s) renders Lectin its application in Forensic Science
(A) Proteinaceous (B) Sensitivity (C) Agglutination (D) Both (A) and (B)
Ans: C
81. All amino acids, except ———— are optically active.
(A) Glycine (B) Alanine (C) Tryptophan (D) All of the above
Ans: A
82. There are no introns in
(A) Animal mt DNA (B) Yeast mt DNA (C) ct DNA in the chloroplast (D) ct DNA of Angiosperms
Ans: A
83. Shine Dalgarno sequences is
(A) Polypurine rich stretch (B) Complementary to a highly conserved sequences of 16S rRNA
(C) Polypyramidine rich stretch (D) Both (A) & (B)
Ans: D
84. Most prokaryotes have a
(A) peptidoglycan cell wall (B) Nucleus (C) Mitochondria (D) Golgi body
Ans: A
85. ‘Knick’ in the polypeptide chain is because of,
(A) Tyrosine (B) Proline (C) Leucine (D) Tryptophan
Ans: B
86. Peptidyl tranferase activity is expressed by
(A) 16S r RNA (B) 18S r RNA (C) 5 S r RNA (D) 23 S r RNA
Ans: D
87. Domains are the units of polypeptides with characteristics of,
(A) Primary lipid that is structurally independent of the other domains in the polypeptide Chain
(B) smallcompact globular protein that is structurally independent of the other Domains in the polypeptide chain
(C) secondary protein that is structurally dependent on the other domains in the Polypeptide chain
(D) tertiary protein that is structurally dependent on the other domains in the polypeptide chain
Ans: B
88. Isoforms are those proteins which are encoded by different genes and perform the same function having,
(A) different tertiary structure (B) same primary structure
(C) different secondary structure (D) different primary structure
Ans: D
89. Cognate tRNAs are
(A) tRNAs accepting one amino acid (B) tRNAs recognized by same synthase
(C) multiple tRNAs representing the same amino acid (D) tRNAs accepting modified amino acids
Ans: B
90. Dactylograpy is
(A) Study of DNA profiling (B) Study of DNA finger printing
(C) Most specific and sensitive for identification (D) Both (B) and (C)
Ans: D
91. The semi conservative nature of DNA replication was confirmed experimentally by
(A) Watson and Crick-1953 (B) Watson and Crick-1958
(C) Meselson and Stahl-1953 (D) Meselson and Stahl-1958
Ans: D
92. The organelle functioning as a semi-autonomous organelle is,
(A) Nucleus (B) Nucleolus (C) Mitochondria (D) Golgi body
Ans: C
93. No longer useful organelles are digested by which organelle?
(A) Ribosomes (B) Lysosomes (C) Chromatin (D) Mitochondria
Ans: B
94. The non-membranous cell structure is,
(A) Chloroplast (B) Mitochondria (C) Ribosome (D) Nucleus
Ans: C
95. DNases cleave DNA target sites at
(A) Both strands of duplex DNA (B) One strand of duplex DNA (C) Terminal ends (D) Both (A) & (B)
Ans: D
96. Which of the following is a chemical nucleotide sequencing method?
(A) Edmans method (B) Sanger method (C) Automated sequencing method (D) Maxam-Gilbert method
Ans: D
97. The smallest virus STNV stands for
(A) Small tobacco necrosis virus (B) Satellite tobacco necrosis virus (C) Small tea necrosis virus (D) Satellite tea necrosis virus
Ans: B
98. Viroids have a signatory feature
(A) Infect plants only (B) Infect lower vertebrates only (C) Imperfectly base paired RNA (D) Imperfectly base paired DNA
Ans: C
99. Basically an RFLP in an SNP that is located in the target site of a
(A) Exonuclease (B) Restriction enzymes (C) Palindrom (D) Endonuclease
Ans: B
100. PCR is using sequencing methods for generating sequence are,
(A) Templates (B) Sanger’s method (C) Sanger’s method and LMPCR (D) None of Above
Ans: D