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PHYSIOLOGY- MEDICAL DEPARTMENT- PAGE 1


PHYSIOLOGY- MEDICAL DEPARTMENT MCQs

​1:-Mechanism by which digitalis increases myocardial contractility is by       
A:-Inhibiting sodium potassium pump        B:-Activating protein kinase       
C:-Decreasing adrenaline levels in myocardium        D:-Decreasing break down of Camp       
Ans: A

2:-Migrating motor complex is initiated by       
A:-Guanylin        B:-Motilin        C:-Peptide YY        D:-Somatostain       
Ans: B

3:-Fluctuations in blood pressure synchronized with respiration are       
A:-Traube Hering Waves        B:-Mayer waves        C:-Slow waves        D:-Gamma oscillations       
Ans: A

4:-Example of a condition which cause distributive shock is       
A:-Hemorrhage        B:-Burns        C:-Anaphylaxis        D:-Tension pneumothorax       
Ans: C

5:-Hyperbaric oxygen therapy is of no use in       
A:-Carbon monoxide poisoning        B:-Gas gansrene        C:-Diabetic leg ulcer        D:-Congestive cardiac failure       
Ans: D

6:-During exercise, arterio venous oxygen difference       
A:-Increases        B:-First decreases then increases        C:-Decreases        D:-Remains same       
Ans: A

7:-The first urge to pass urine is felt as urinary bladder volume of       
A:-100 ml        B:-150 ml        C:-250 ml        D:-300 ml       
Ans: B

8:-All of the following are effects of prolonged stay in space EXCEPT       
A:-Decrease in red cell mass        B:-Loss of bone mass        C:-Increase in blood volume        D:-Decrease in muscle strength       
Ans: C

9:-Which of the following diuretic acts on proximal tubule?       
A:-Spironolactone        B:-Amiloride        C:-Frusemide        D:-Acetazolamide       
Ans: D

10:-Which of the following increases extracellular potassium concentration?       
A:-Insulin        B:-Aldosterone        C:-Alkalosis        D:-Severe exercise       
Ans: D

11:-Which of the following is NOT a component of Papez circuit?       
A:-Cingulate gyrus        B:-Mammilary body        C:-Posterior thalamic nucleus        D:-Hippocampus       
Ans: C

12:-A mutation in KALIG1 gene is seen in       
A:-Kartagener's syndrome       
B:-Kallmann syndrome       
C:-Klinfelter's syndrome

D:-Kluver Bucy syndrome       
Ans: B

13:-The protein which connects Z line to M line and provides scaffolding for sarcomere is       
A:-Titin        B:-Desmin        C:-Actinin        D:-Troponin       
Ans: A

14:-The average arm to tongue circulation time is       
A:-5 seconds        B:-10 seconds        C:-15 seconds        D:-20 second       
Ans: C

15:-Human Chorionic Gonadotropin acts on       
A:-LH receptor        B:-FSH receptor        C:-TSH receptor        D:-ACTH receptor       
Ans: A

16:-Effect of deafferentation of bladder is        
A:-Shrunken and hypertrophied wall        B:-Spastic with hyperactive voiding reflex       
C:-Overfilled with dribbling        D:-Distended, thin walled and hypotonic       
Ans: D

17:-The diluting segment of nephron is       
A:-Proximal convoluted tubule        B:-Thick ascending limb of loop of Henle       
C:-Descending limb of loop of Henle        D:-Medullary collecting duct       
Ans: B

18:-Oral contraceptive pills act by       
A:-Inhibiting ovulation        B:-Decreasing motility of sperms        C:-Spermicidal action        D:-Increasing motility of fallopian tubes       
Ans: A

19:-The Poiseuille Hagen formula calculates relation among the following EXCEPT       
A:-Flow in a narrow tube

B:-pH of blood       
C:-Raidus of the tube       
D:-Viscosity of blood       
Ans: B

20:-Gap junctions are made up of proteins called       
A:-Connexons        B:-Caspases        C:-Dyneins        D:-Cadherins       
Ans: A

21:-Which of the following proteins are called as folding proteins?       
A:-Perforins        B:-Chaperons        C:-Tubulins        D:-Clathrins       
Ans: B

22:-Enzyme which converts testosterone to estradiol in ovarian follicle is       
A:-Isomerase        B:-Dehydrogenase        C:-Aromatase        D:-Transferase       
Ans: C

23:-Fusion of sperm with membrane of ovum is mediated by       
A:-Acrosin        B:-Fertilin        C:-Catsper        D:-Inhibin       
Ans: B

24:-The main excitatory neurotransmitter in central nervous system is       
A:-Glutamate        B:-Substance P        C:-Enkephalin        D:-Serotonin       
Ans: A

25:-Bicarbonate reabsorption is maximum in       
A:-Medullary collecting duct        B:-Distal convoluted tubule        C:-Proximal convoluted tubule        D:-Cortical collecting duct       
Ans: C

26:-Fibres from ipsilateral hemiretina project in which layer of lateral geniculate body       
A:-1,4,6        B:-2,3,5        C:-1,3,6        D:-2,4,6       
Ans: B

27:-All of the following are dopamine agonists EXCEPT       
A:-Bromocriptine        B:-Apomorphine        C:-Clozapine        D:-Pramiprexole       
Ans: C

28:-The inclusion bodies seen in neurons of parkinsonism patients are       
A:-Lewy bodies        B:-Russell bodies        C:-Negri bodies        D:-Schaumann bodies       
Ans: A

29:-The substance that is present both in serum and plasma is       
A:-Prothrombin        B:-Antihaemophilic factor A        C:-Fibrinogen        D:-Proconvertin       
Ans: D

30:-An agent which causes contraction of mesangial cells is       
A:-Atrial natriuretic peptide        B:-Dopamine        C:-cAMP        D:-Endothelins       
Ans: D

31:-Cerebellar nystagmus occurs due to damage to       
A:-Anterior lobe        B:-Flocculonodular lobe        C:-Posterior lobe        D:-Vermis       
Ans: B

32:-Type of cell NOT present in olfactory bulb       
A:-Mitral cell       
B:-Granule cell       
C:-Tufted cell
D:-Horizontal cell       
Ans: D

33:-Which of the following is increased when radius of resistance vessels is increased?       
A:-Haematocrit        B:-Diastolic blood pressure        C:-Capillary blood flow        D:-Systolic blood pressure       
Ans: C

34:-Which of the following is NOT a cause of edema?       
A:-Decreased capillary permeability        B:-Decreased plasma protein       
C:-Increased venous pressure        D:-Inadequate lymph flow       
Ans: A

35:-Dicrotic notch in aortic pressure curve is caused by closure of       
A:-Tricuspid valve        B:-Pulmonary valve        C:-Mitral valve        D:-Aortic valve       
Ans: D

36:-Fourth heart sounds is caused by       
A:-Closure of aortic and pulmonary valve        B:-Ventricular filling       
C:-Closure of mitral and tricuspid valve        D:-Vibrations in ventricular wall during systole       
Ans: B

37:-Largest volume of gas that can be moved into and out of the lungs in one minute by voluntary effort is       
A:-Respiratory minute volume        B:-Forced vital capacity       
C:-Maximum voluntary ventilation        D:-Total lung capacity       
Ans: C

38:-Which of the following plays a major role in vasodilatation of penis during erection?       
A:-Nitric oxide        B:-Vasopressin        C:-Bradykinin        D:-Prostaglandin       
Ans: A

39:-Sensory system codes for the following attributes of a stimulus EXCEPT       
A:-Modality         B:-Sensitization        C:-Intensity        D:-Location       
Ans: B

40:-Which of the following is NOT a characteristic of smooth muscle?       
A:-Slow cycling of myosin cross bridges        B:-Low energy requirement to sustain contraction       
C:-Stress relaxation        D:-Maximum force of contraction is less than that of skeletal muscle       
Ans: D

41:-Duration of AV nodal delay is       
A:-0.1 seconds        B:-0.3 seconds        C:-0.5 seconds        D:-0.7 seconds       
Ans: A

42:-Second polar body is extruded       
A:-At the time of ovulation        B:-At the time of LH surge       
C:-At the time of fertilization of the ovum        D:-48 hours prior to ovulation       
Ans: C

43:-Compound action potential is the property of       
A:-Sensory nerve        B:-Mixed nerve        C:-Single nerve fibre        D:-Motor nerve       
Ans: B

44:-The wheal in triple response occurs due to       
A:-increased capillary permeability        B:-arteriolar dilation        C:-axon reflex        D:-contraction of precapillary sphincters       
Ans: A

45:-Which of the following has the highest pH?       
A:-Saliva        B:-Gastric juice        C:-Gall bladder bile        D:-Pancreatic juice       
Ans: D

46:-EEG rhythm with lowest frequency is       
A:-Alpha        B:-Beta        C:-Delta        D:-Theta       
Ans: C

47:-Effective renal plasma flow in humans is       
A:-425 ml/min        B:-525 ml/min        C:-625 ml/min        D:-725 ml/min       
Ans: C

48:-Group A nerve fibres are most susceptible to       
A:-Pressure        B:-Hypoxia        C:-Temperature        D:-Local anaesthetics       
Ans: A

49:-Which of the following is a peptide hormone?       
A:-Estrogen        B:-Parathormone        C:-Thyroxine        D:-Cortisol       
Ans: B

50:-Sperms persist in female genital tract for       
A:-1-2 minutes        B:-1-2 hours        C:-1-2 days        D:-1-2 weeks       
​Ans: C
​51:-Water reabsorption is maximum from       
A:-duodenum        B:-colon        C:-ileum        D:-jejunum       
Ans: D

52:-The most abundant cell type in Islets of Langerhans is       
A:-A       
B:-B       
C:-D

D:-F       
Ans: A

53:-Work done in quiet breathing is       
A:-0.1 kg-m/min        B:-1.2 kg-m/min        C:-0.5 kg-m/min        D:-3.5 kg-m/min       
Ans: C

54:-Conversion of fibrinogen to fibrin is catalysed by        
A:-Thromboplastin        B:-Stuart Prower Factor        C:-Proconvertin        D:-Thrombin       
Ans: D

55:-Which of the following causes a right shift of oxygen dissociation curve?       
A:-Decrease in body temperature        B:-Foetal haemoglobin        C:-Myoglobin        D:-Decrease in blood pH       
Ans: D

56:-Which of the following is NOT an example of syndromic deafness?       
A:-Liddle's syndrome        B:-Pendred syndrome        C:-Long QT syndrome        D:-Bartter syndrome       
Ans: A

​57:-Which sensation is not lost on the same side of lesion in Brown Sequard Syndrome?       
A:-Position sense        B:-Vibration        C:-Temperature        D:-Touch       
Ans: C

58:-Heavy water is used to determine       
A:-Intracellular fluid volume        B:-Extracellular fluid volume        C:-Plasma volume        D:-Total body water       
Ans: D

59:-Spermatozoa acquire motility in       
A:-Vas deferens
       B:-Epidydimis        C:-Rete testis        D:-Prostate       
Ans: B

60:-Functional residual capacity in male is       
A:-2.2 L        B:-3.2 L        C:-4.2 L        D:-5.2 L       
Ans: A

61:-Glial cells which help in making Blood brain barrier are       
A:-Oligo dendrocytes        B:-Schwann cells        C:-Astrocytes        D:-Microglia       
Ans: C

62:-Weber Fechner law deals with       
A:-Receptive field organization        B:-Intensity discrimination        C:-Tactile localization        D:-None       
Ans: B

63:-Which of the following is an Orexigenic factor?       
A:-Corticotropin releasing hormone        B:-Glucagon        C:-Leptin        D:-Neuropeptide Y       
Ans: D

64:-Stokes Adams syndrome is loss of consciousness following       
A:-Ventricular fibrillation        B:-Complete heart block        C:-Myocardial infarction        D:-Ventricular tachycardia       
Ans: B

65:-Effect of storage of blood on RBCs are all EXCEPT       
A:-RBCs become spherical        B:-Depletion of ATP        C:-Loss of membrane stability        D:-Increased glycolysis       
Ans: D

66:-Prosapagnosia is the inability to       
A:-Draw straight lines        B:-Recognize faces        C:-Count in order        D:-Perceive pain       
Ans: B

67:-Which of the following is facilitatory to stretch reflex?       
A:-Vestibular nucleus        B:-Cerebellum        C:-Motor cortex        D:-Basal ganglia       
Ans: A

68:-Betz cells are found in       
A:-Thalamus        B:-Hypothalamus        C:-Motor cortex        D:-Sensory cortex       
Ans: C

69:-Gastric acid secretion is stimulated by all EXCEPT       
A:-Acetyl choline        B:-Histamine        C:-Secretin        D:-Gastrin       
Ans: C

70:-Lesion in angular gyrus produces       
A:-Motor aphasia        B:-Sensory aphasia        C:-Conductive aphasia        D:-Anomic aphasia      
  Ans: D

71:-The blobs of visual cortex are associated with       
A:-Colour processing        B:-Orientation        C:-Ocular movements        D:-Ocular dominance       
Ans: A

72:-Which of the following is an example of a trinucleotide repeat disease?       
A:-Wilson's disease        B:-Cystic fibrosis        C:-Hereditary spherocytosis
       D:-Huntington's disease       
Ans: D

73:-Muscle weakness caused by antibodies against calcium channels in nerve endings at neuromuscular junction is seen in       
A:-Myaesthenia gravis        B:-Lambert Eaton syndrome        C:-Multiple sclerosis        D:-Muscular dystrophy       
Ans: B

74:-K cells of intestine secrete       
A:-Secretin        B:-Vasoactive Intenstinal Pepide        C:-Gastric Inhibitory Peptide        D:-Cholecystokinin       
Ans: C

75:-All are produced by kidney EXCEPT       
A:-Vitamin D        B:-Renin        C:-Erythropoietin        D:-Aldosterone       
Ans: D

76:-The principal buffer in interstitial fluid is       
A:-Carbonic acid        B:-Phosphate        C:-Haemoglobin        D:-Ammonia       
Ans: A

77:-Blood flow is almost always turbulent when Reynold's number is more than       
A:-2000        B:-3000        C:-4000        D:-5000       
Ans: B

78:-Respiratory burst in neutrophil is due to       
A:-NADH oxidase        B:-Elastase        C:-Myeloperoxidase        D:-NADPH oxidase       
Ans: D

79:-Cholagogues are substances which cause       
A:-Increases biliary secretion from liver
       B:-Neutralizes acid chyme       
C:-Contraction of gall bladder        D:-Helps in absorption of fat soluble vitamins       
Ans: C

80:-Bicarbonate in gastric mucosal barrier is secreted from       
A:-Chief cells        B:-Oxyntic cells        C:-Surface mucosal cells        D:-Neck cells       
​ Ans: C 

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