PHARMACY
PHARMACY SYLLABUS
(These syllabus may change from time to time. Please check with the relevant Public Service Commission websites for any changes in the syllabus)
Part I
Natural products: Definition, classification and brief chemistry of alkaloids, glycosides, terpenoids, volatile oils, tannins, resins etc. Biological source, constituents, identification tests and pharmacological uses of Cinchona, cinnamon, castor oil, cardamom, ginger, opium, clove, peppermint oil, honey, fennel and nutmeg .
Part II
Chemistry in Everyday life: Definition, classification, brief chemistry, mechanism of action and therapeutic uses of analgesics, antipyretics, anti-inflammatory agents, hypnotics and sedatives, narcotics and psychotropic drugs, anaesthetics, antiseptics and disinfectants, antihistamines, antihypertensive drugs, anti-diabetic drugs, cosmetics. Dyes-different types and examples.
Part III
Biomolecules: Definition, classification, brief chemistry, qualitative tests and metabolism of carbohydrate, protein and lipids. Deficiency diseases and diseases related to their metabolism Classification of amino acids. Brief chemistry and role of vitamins and coenzymes. Enzymes, Minerals, Hormones, DNA, RNA.
Part IV
Quality control of Pharmaceuticals: Sources of impurities in Pharmaceuticals, Purification methods of Pharmaceuticals, test for purity, limit tests for arsenic, lead, sulphate, chloride, iron and heavy metals.
Part V
General Chemistry Stoichiometry, Chemical bonding, Periodic properties, States of matter, Solutions, chemical kinetics, Thermodynamics, Electro chemistry.
Part VI
Organic chemistry Hydrocarbons, cycloalkanes, physical properties, functional groups, IUPAC nomenclature, concept of aromaticity, Stereochemistry of organic compounds.
Part VII
Environmental Chemistry Pollution- soil, water, air pollutants. Greenhouse effect, acid rain, ozone depletion, industrial and nuclear waste, Polymers- different types, examples and effect on environment. Soaps and detergents, Water treatment, Green chemistry
Part VIII
Analytical chemistry Acids and bases, buffers, water analysis, qualitative analysis of anions and systematic analysis of cations. Principle of titrations- acidimetry, redox, Complexometry, precipitation titrations. Principle of UV-Visible spectroscopy, IR spectroscopy, NMR, mass spectrometry.
Part I
Natural products: Definition, classification and brief chemistry of alkaloids, glycosides, terpenoids, volatile oils, tannins, resins etc. Biological source, constituents, identification tests and pharmacological uses of Cinchona, cinnamon, castor oil, cardamom, ginger, opium, clove, peppermint oil, honey, fennel and nutmeg .
Part II
Chemistry in Everyday life: Definition, classification, brief chemistry, mechanism of action and therapeutic uses of analgesics, antipyretics, anti-inflammatory agents, hypnotics and sedatives, narcotics and psychotropic drugs, anaesthetics, antiseptics and disinfectants, antihistamines, antihypertensive drugs, anti-diabetic drugs, cosmetics. Dyes-different types and examples.
Part III
Biomolecules: Definition, classification, brief chemistry, qualitative tests and metabolism of carbohydrate, protein and lipids. Deficiency diseases and diseases related to their metabolism Classification of amino acids. Brief chemistry and role of vitamins and coenzymes. Enzymes, Minerals, Hormones, DNA, RNA.
Part IV
Quality control of Pharmaceuticals: Sources of impurities in Pharmaceuticals, Purification methods of Pharmaceuticals, test for purity, limit tests for arsenic, lead, sulphate, chloride, iron and heavy metals.
Part V
General Chemistry Stoichiometry, Chemical bonding, Periodic properties, States of matter, Solutions, chemical kinetics, Thermodynamics, Electro chemistry.
Part VI
Organic chemistry Hydrocarbons, cycloalkanes, physical properties, functional groups, IUPAC nomenclature, concept of aromaticity, Stereochemistry of organic compounds.
Part VII
Environmental Chemistry Pollution- soil, water, air pollutants. Greenhouse effect, acid rain, ozone depletion, industrial and nuclear waste, Polymers- different types, examples and effect on environment. Soaps and detergents, Water treatment, Green chemistry
Part VIII
Analytical chemistry Acids and bases, buffers, water analysis, qualitative analysis of anions and systematic analysis of cations. Principle of titrations- acidimetry, redox, Complexometry, precipitation titrations. Principle of UV-Visible spectroscopy, IR spectroscopy, NMR, mass spectrometry.
PHARMACY MCQs
1:-Common adverse effect of thrombolytics
A:-Bleeding
B:-Unstable angina
C:-Arterial occlusion
D:-Myocardial infarction
Ans: A
2:-Citral is the major constituent of
A:-Turpentine oil
B:-Lemon grass oil
C:-Peppermint oil
D:-Cardamom oil
Ans: B
3:-The dosage form in which fluid containing the drug is retained in the rectum for the drug to act either locally or systemically
A:-Retention enema
B:-Suppositories
C:-Evacuant enema
D:-Lotion
Ans: A
4:-Semisolid dosage forms with high percentage of insoluble solid medicaments
A:-Creams
B:-Pastes
C:-Gels
D:-Jellies
Ans: B
5:-Coriander leaves are rich source of
A:-Vitamin A
B:-Volatile oil
C:-Geraniol
D:-Pinene
Ans: A
6:-Convenient dosage form to deliver pellets or granular material orally
A:-Hard gelatin capsule
B:-Soft gelatin capsule
C:-Layered tablets
D:-Compressed tablets
Ans: A
7:-In economic order quantity, which of the following should be minimum ?
A:-Ordering cost and carrying cost
B:-Ordering cost
C:-Carrying cost
D:-Ordering quantity
Ans: A
8:-Which of the following is an oleo gum resin ?
A:-Myrrh
B:-Storax
C:-Colocynth
D:-Colophony
Ans: A
9:-The breakdown of a tablet into smaller particles or granules is known as
A:-Disintegration
B:-Crushing
C:-Dissolution
D:-Granulation
Ans: A
10:-The extent to which a patient's medication taking behaviour coincides with the intention of health advice is known as
A:-Monitoring
B:-Adherence
C:-Drug utilization
D:-Purchasing power
Ans: B
11:-Glycoside present in Nux vomica
A:-Strichnine
B:-Loganine
C:-Ecgonine
D:-Quinovine
Ans: B
12:-Which of the following uses the violent turbulence of the air and steam to reduce the particle size by inter particular attrition ?
A:-Cutting mill
B:-Fluid energy mill
C:-Roller mill
D:-Colloid mill
Ans: B
13:-Which among the following is a phase II reaction of drug metabolism ?
A:-Oxidation
B:-Conjugation
C:-Reduction
D:-Hydrolysis
Ans: B
14:-The equipment used for moist heat sterilization
A:-Hot air oven
B:-Cartridge filter
C:-Autoclave
D:-Cyclone separator
Ans: C
15:-Which of the following technique is used to increase the solubility of weak electrolytes and non-polar molecules by the addition of a water miscible solvent in which the drug has good solubility ?
A:-Complexation
B:-Solubilization
C:-Hydrotrophy
D:-Co solvency
Ans: D
16:-The most important influence of temperature on emulsion stability
A:-Creaming
B:-Caking
C:-Cracking
D:-Phase inversion
Ans: D
17:-Green vitriol is known as
A:-Copper sulphate
B:-Ferric ammonium citrate
C:-Ferrous sulphate
D:-Ferrous gluconate
Ans: C
18:-The approved indication of Lurasidone
A:-Depression
B:-Mania
C:-Parkinsonism
D:-Schizophrenia
Ans: D
19:-One fluid ounce volume is equal to
A:-45.57 ml
B:-60.57 ml
C:-15.57 ml
D:-29.57 ml
Ans: D
20:-Boiling water is poured over the drug and allowing to keep in contact with the drug for 15 minutes with occasional stirring and finally filtered off without pressing the marc. This process is known as
A:-Maceration
B:-Infusion
C:-Percolation
D:-Decoction
Ans: B
A:-Bleeding
B:-Unstable angina
C:-Arterial occlusion
D:-Myocardial infarction
Ans: A
2:-Citral is the major constituent of
A:-Turpentine oil
B:-Lemon grass oil
C:-Peppermint oil
D:-Cardamom oil
Ans: B
3:-The dosage form in which fluid containing the drug is retained in the rectum for the drug to act either locally or systemically
A:-Retention enema
B:-Suppositories
C:-Evacuant enema
D:-Lotion
Ans: A
4:-Semisolid dosage forms with high percentage of insoluble solid medicaments
A:-Creams
B:-Pastes
C:-Gels
D:-Jellies
Ans: B
5:-Coriander leaves are rich source of
A:-Vitamin A
B:-Volatile oil
C:-Geraniol
D:-Pinene
Ans: A
6:-Convenient dosage form to deliver pellets or granular material orally
A:-Hard gelatin capsule
B:-Soft gelatin capsule
C:-Layered tablets
D:-Compressed tablets
Ans: A
7:-In economic order quantity, which of the following should be minimum ?
A:-Ordering cost and carrying cost
B:-Ordering cost
C:-Carrying cost
D:-Ordering quantity
Ans: A
8:-Which of the following is an oleo gum resin ?
A:-Myrrh
B:-Storax
C:-Colocynth
D:-Colophony
Ans: A
9:-The breakdown of a tablet into smaller particles or granules is known as
A:-Disintegration
B:-Crushing
C:-Dissolution
D:-Granulation
Ans: A
10:-The extent to which a patient's medication taking behaviour coincides with the intention of health advice is known as
A:-Monitoring
B:-Adherence
C:-Drug utilization
D:-Purchasing power
Ans: B
11:-Glycoside present in Nux vomica
A:-Strichnine
B:-Loganine
C:-Ecgonine
D:-Quinovine
Ans: B
12:-Which of the following uses the violent turbulence of the air and steam to reduce the particle size by inter particular attrition ?
A:-Cutting mill
B:-Fluid energy mill
C:-Roller mill
D:-Colloid mill
Ans: B
13:-Which among the following is a phase II reaction of drug metabolism ?
A:-Oxidation
B:-Conjugation
C:-Reduction
D:-Hydrolysis
Ans: B
14:-The equipment used for moist heat sterilization
A:-Hot air oven
B:-Cartridge filter
C:-Autoclave
D:-Cyclone separator
Ans: C
15:-Which of the following technique is used to increase the solubility of weak electrolytes and non-polar molecules by the addition of a water miscible solvent in which the drug has good solubility ?
A:-Complexation
B:-Solubilization
C:-Hydrotrophy
D:-Co solvency
Ans: D
16:-The most important influence of temperature on emulsion stability
A:-Creaming
B:-Caking
C:-Cracking
D:-Phase inversion
Ans: D
17:-Green vitriol is known as
A:-Copper sulphate
B:-Ferric ammonium citrate
C:-Ferrous sulphate
D:-Ferrous gluconate
Ans: C
18:-The approved indication of Lurasidone
A:-Depression
B:-Mania
C:-Parkinsonism
D:-Schizophrenia
Ans: D
19:-One fluid ounce volume is equal to
A:-45.57 ml
B:-60.57 ml
C:-15.57 ml
D:-29.57 ml
Ans: D
20:-Boiling water is poured over the drug and allowing to keep in contact with the drug for 15 minutes with occasional stirring and finally filtered off without pressing the marc. This process is known as
A:-Maceration
B:-Infusion
C:-Percolation
D:-Decoction
Ans: B
21:-Drug of choice for the management of status epilepticus
A:-Ethosuximide
B:-50% glucose
C:-Diazepam
D:-Sodium valproate
Ans: C
22:-Pharmacy bill introduced by government of India in the year
A:-1948
B:-2016
C:-1940
D:-1945
Ans: D
23:-Which of the following is a nutritional deficiency disorder ?
A:-Mumps
B:-Marasmus
C:-Mycoses
D:-Myelitis
Ans: B
24:-The immunoglobulin present in very low concentration in normal serum
A:-Ig E
B:-Ig M
C:-Ig G
D:-Ig A
Ans: A
25:-Condition in which WBC is significantly lower than the reference range
A:-Pancytopenia
B:-Leucocytosis
C:-Leucopenia
D:-Neutropenia
Ans: C
26:-The science deals with the interaction of exogenously administered chemical molecules with living system
A:-Anthropology
B:-Bioinformatics
C:-Cheminformatics
D:-Pharmacology
Ans: D
27:-According to Indian Pharmacopoeia the statement of sparingly soluble at 20° to 30° means approximate volume of solvent in ml per gm of solute is
A:-From 1 to 10
B:-From 30 to 100
C:-From 10 to 30
D:-From 100 to 1000
Ans: B
28:-Chief constituent of Bael fruit is
A:-Marmelosin
B:-Marmesin
C:-Mannitol
D:-Mannoglycan
Ans: A
29:-Dopamine agonist used in the treatment of Parkinsonism
A:-Selegiline
B:-Entacapone
C:-Bromocriptine
D:-Amantadine
Ans: C
30:-Viscous liquid preparations used orally for the relief of cough
A:-Gargles
B:-Drops
C:-Elixirs
D:-Linctuses
Ans: D
31:-Schedule Y of D&C Act, 1945 deals with
A:-Generic drugs
B:-Prescription drugs
C:-Clinical trial
D:-Medical devices
Ans: C
32:-Permanent contraceptive method
A:-Intrauterine devices
B:-Depot formulations
C:-Non-scalpel vasectomy
D:-Menstrual induction
Ans: C
33:-An ultra filtrate of plasma formed by the choroid plexus is
A:-Cerebrospinal fluid
B:-Amniotic fluid
C:-Interstitial fluid
D:-Serum
Ans: A
34:-Irritant drugs are not given by
A:-Intramuscularly
B:-Topically
C:-Subcutaneously
D:-Intravenously
Ans: C
35:-Along with benzoic acid Whitfield's ointment contains
A:-6% salicylic acid
B:-2% salicylic acid
C:-4% salicylic acid
D:-3% salicylic acid
Ans: D
36:-Which among the following is stored in light resistant container ?
A:-Albendazole
B:-Allopurinol
C:-Adrenaline
D:-Alprazolam
Ans: C
37:-Which of the following is not an adverse effect of propranolol ?
A:-Lactic acidosis
B:-Depression
C:-Bronchospasm
D:-Hypotension
Ans: A
38:-Water soluble portion of tragacanth
A:-Bassorin
B:-Tragacanthin
C:-Alginate
D:-Agaropectin
Ans: B
39:-Which among the followings do not have an active metabolite ?
A:-Morphine
B:-Neostigmine
C:-Diazepam
D:-Digitoxin
Ans: B
40:-In filtration anesthesia to prolong the duration of action procaine is mixed with
A:-Glycine
B:-Procainamide
C:-Cocaine
D:-Adrenaline
Ans: D
41:-According to NDPS Act, 1985 cultivating coca plant or gathering any portion of coca plant is termed as
A:-Production
B:-Illicit traffic
C:-Preparation
D:-Manufacture
Ans: B
42:-Macrocytic anaemia developed due to the deficiency of intrinsic factor is known as
A:-Pernicious anaemia
B:-Magaloblastic anaemia
C:-Hypochromic anaemia
D:-Sideroblastic anaemia
Ans: A
43:-Which of the following is used to ligate large blood vessels ?
A:-Aneurism clip
B:-Foley's catheter
C:-Splint
D:-Umbilical tape
Ans: D
44:-Theophylline is a non-competitive inhibitor of
A:-Phosphodiesterase
B:-Peroxidase
C:-Aldehyde dehydrogenase
D:-Carbonic anhydrase
Ans: A
45:-Intracellular enzyme which is a combination of heme and protein and act as catalyst in biological oxidation are termed as
A:-Hemoglobin
B:-Cytochromes
C:-Creatine kinase
D:-Transferrin
Ans: B
46:-Aminophylline is a stable mixture of theophylline with which of the following ?
A:-Aminocaproic acid
B:-Amiloride
C:-Ethyl oleate
D:-Ethylene diamine
Ans: D
47:-The pharmacokinetic parameter that describes the efficiency of elimination of drug from the body is
A:-Half life
B:-Clearance
C:-Excretion
D:-Metabolism
Ans: B
48:-Drug containing saponin glycoside as major constituent
A:-Cascara
B:-Ginko
C:-Brahmi
D:-Quassia
Ans: C
49:-Which of the following is an additive drug combination ?
A:-Amlodipine + Atenolol
B:-Histamine + Adrenaline
C:-Sulphamethoxazole + Trimethoprime
D:-Tyramine + MAO inhibitors
Ans: A
50:-5-HT antagonist used to control chemotherapy induced nausea and vomiting
A:-Risperidone
B:-Ondansetrone
C:-Cyproheptadine
D:-Clozapine
Ans: B
51:-Cardioselective beta blocker
A:-Propranolol
B:-Timolol
C:-Carvedilol
D:-Metoprolol
Ans: D
52:-Synthetic Cannabinoid
A:-Methadone
B:-Tramadol
C:-Naloxone
D:-Nabilone
Ans: D
53:-Most abundant cation in the extra cellular fluid
A:-Potassium
B:-Calcium
C:-Sodium
D:-Chloride
Ans: C
54:-The Medicinal and Toilet Preparations Act came in to force in
A:-1957
B:-1967
C:-1958
D:-1968
Ans: A
55:-Class I B antiarrhythmic drug
A:-Disopyramide
B:-Amiodarone
C:-Lidocaine
D:-Verapamil
Ans: C
56:-Causative organism of Plague
A:-Arbovirus
B:-Rat flea
C:-Clostridium tetani
D:-Yersinia pestis
Ans: D
57:-All enzymes involved in glycolysis are present in
A:-Mitochondria
B:-Blood
C:-Cytosol
D:-Cellwall
Ans: C
58:-The normal range of serum potassium level
A:-96-106 mEq/L
B:-1.5-2.2 mEq/L
C:-136-145 mEq/L
D:-3.5-5.0 mEq/L
Ans: D
59:-Water purified by distillation or reverse osmosis and meets the specifications for purity as per IP which is free from pyrogens and not intended to be sterile is
A:-Purified water
B:-Sterile water for injection
C:-Deionized water
D:-Water for injection
Ans: D
60:-The desirable level of total serum cholesterol in adults
A:-Less than 200 mg/dL
B:-Less than 240 mg/dL
C:-More than 200 mg/dL
D:-More than 240 mg/dL
Ans: A
61:-Which of the following is mainly used as a diuretic ?
A:-Ginseng
B:-Mustard
C:-Ginko
D:-Gokhru
Ans: D
62:-Tissue amine widely distributed in plants animals and in the venom of bees and wasps
A:-Serotonine
B:-Tyramine
C:-Histamine
D:-Adrenaline
Ans: C
63:-An indication of renal function which is used to estimate glomerular filtration rate is
A:-Serum urea
B:-Serum alkaline phosphatase
C:-Blood urea nitrogen
D:-Serum creatinine
Ans: D
64:-Inadequate blood flow to a part of the body secondary to constriction or blockage of the supplying artery
A:-Infarction
B:-Ischemia
C:-Necrosis
D:-Eclampsia
Ans: B
65:-Which among the following is an analytical agency constituted for efficient administration of D&C Act
A:-Central Drugs Laboratory
B:-Controlling Authority
C:-DTAB
D:-Drugs Consultative Committee
Ans: A
66:-A toxoid vaccine is
A:-Detoxicated endotoxin
B:-Detoxicated cellular fraction
C:-Detoxicated exotoxin
D:-Antitoxin
Ans: C
67:-The difference that exists between the intake and output of nitrogen both being expressed in terms of grams N per day is
A:-Blood Urea Nitrogen
B:-Non-Nitrogen Protein
C:-Protein Nitrogen
D:-Nitrogen balance
Ans: D
68:-Which of the following is a book of secondary entry ?
A:-Cash book
B:-Two column cash book
C:-Ledger
D:-Journal
Ans: C
69:-The ability of sulphides in highly alkaline pH to reduce the disulphide linkage in the aminoacid cysteine is the principle behind
A:-Sulphur candles
B:-Sulphite preservatives
C:-Sulphide depilatories
D:-Sulphate antidotes
Ans: C
70:-Which of the following is deficient in Vitamin D ?
A:-Cod liver oil
B:-Halibut oil
C:-Eggs
D:-Shark liver oil
Ans: D
71:-Which of the following monoclonal antibody is fully human origin ?
A:-Daclizumab
B:-Infliximab
C:-Adalimumab
D:-Edrecolomab
Ans: C
72:-The assets and liabilities of a business organization is
A:-Profit and loss account
B:-Balance Sheet
C:-Trial balance
D:-Debentures
Ans: B
73:-Centrally acting cough suppressant
A:-Ambroxolol
B:-Codeine
C:-Bromhexine
D:-Ammonium bicarbonate
Ans: B
74:-Which of the following is preferred for dressing wounds infected with pyogenic bacteria ?
A:-Magsulf
B:-Eusol
C:-AF lotion
D:-Mercurochrome solution
Ans: B
75:-The quantity of sodium chloride required to prepare 400 ml of 0.9% solution
A:-2.6 gm
B:-3.25 gm
C:-3.6 gm
D:-2.25 gm
Ans: C
76:-Aminoacid present in high concentration in brain tissues
A:-Glutamic acid
B:-Lysine
C:-Arginine
D:-Proline
Ans: A
77:-Locally applied protein precipitants with low cell permeability are known as
A:-Epilatories
B:-Astringents
C:-Humactants
D:-Keratolytics
Ans: B
78:-Metal cylinders filled with nitrous oxide for hospital use is painted in
A:-Blue
B:-Grey
C:-White
D:-Black
Ans: A
79:-Which of the following is not a legal requirement for opening a drug store ?
A:-Location
B:-Minimum space
C:-Drug licence
D:-Store arrangements
Ans: A
80:-Lanolin is also known as
A:-Carnauba wax
B:-Anhydrous wool fat
C:-Hydrous wool fat
D:-Spermaceti
Ans: C
A:-Ethosuximide
B:-50% glucose
C:-Diazepam
D:-Sodium valproate
Ans: C
22:-Pharmacy bill introduced by government of India in the year
A:-1948
B:-2016
C:-1940
D:-1945
Ans: D
23:-Which of the following is a nutritional deficiency disorder ?
A:-Mumps
B:-Marasmus
C:-Mycoses
D:-Myelitis
Ans: B
24:-The immunoglobulin present in very low concentration in normal serum
A:-Ig E
B:-Ig M
C:-Ig G
D:-Ig A
Ans: A
25:-Condition in which WBC is significantly lower than the reference range
A:-Pancytopenia
B:-Leucocytosis
C:-Leucopenia
D:-Neutropenia
Ans: C
26:-The science deals with the interaction of exogenously administered chemical molecules with living system
A:-Anthropology
B:-Bioinformatics
C:-Cheminformatics
D:-Pharmacology
Ans: D
27:-According to Indian Pharmacopoeia the statement of sparingly soluble at 20° to 30° means approximate volume of solvent in ml per gm of solute is
A:-From 1 to 10
B:-From 30 to 100
C:-From 10 to 30
D:-From 100 to 1000
Ans: B
28:-Chief constituent of Bael fruit is
A:-Marmelosin
B:-Marmesin
C:-Mannitol
D:-Mannoglycan
Ans: A
29:-Dopamine agonist used in the treatment of Parkinsonism
A:-Selegiline
B:-Entacapone
C:-Bromocriptine
D:-Amantadine
Ans: C
30:-Viscous liquid preparations used orally for the relief of cough
A:-Gargles
B:-Drops
C:-Elixirs
D:-Linctuses
Ans: D
31:-Schedule Y of D&C Act, 1945 deals with
A:-Generic drugs
B:-Prescription drugs
C:-Clinical trial
D:-Medical devices
Ans: C
32:-Permanent contraceptive method
A:-Intrauterine devices
B:-Depot formulations
C:-Non-scalpel vasectomy
D:-Menstrual induction
Ans: C
33:-An ultra filtrate of plasma formed by the choroid plexus is
A:-Cerebrospinal fluid
B:-Amniotic fluid
C:-Interstitial fluid
D:-Serum
Ans: A
34:-Irritant drugs are not given by
A:-Intramuscularly
B:-Topically
C:-Subcutaneously
D:-Intravenously
Ans: C
35:-Along with benzoic acid Whitfield's ointment contains
A:-6% salicylic acid
B:-2% salicylic acid
C:-4% salicylic acid
D:-3% salicylic acid
Ans: D
36:-Which among the following is stored in light resistant container ?
A:-Albendazole
B:-Allopurinol
C:-Adrenaline
D:-Alprazolam
Ans: C
37:-Which of the following is not an adverse effect of propranolol ?
A:-Lactic acidosis
B:-Depression
C:-Bronchospasm
D:-Hypotension
Ans: A
38:-Water soluble portion of tragacanth
A:-Bassorin
B:-Tragacanthin
C:-Alginate
D:-Agaropectin
Ans: B
39:-Which among the followings do not have an active metabolite ?
A:-Morphine
B:-Neostigmine
C:-Diazepam
D:-Digitoxin
Ans: B
40:-In filtration anesthesia to prolong the duration of action procaine is mixed with
A:-Glycine
B:-Procainamide
C:-Cocaine
D:-Adrenaline
Ans: D
41:-According to NDPS Act, 1985 cultivating coca plant or gathering any portion of coca plant is termed as
A:-Production
B:-Illicit traffic
C:-Preparation
D:-Manufacture
Ans: B
42:-Macrocytic anaemia developed due to the deficiency of intrinsic factor is known as
A:-Pernicious anaemia
B:-Magaloblastic anaemia
C:-Hypochromic anaemia
D:-Sideroblastic anaemia
Ans: A
43:-Which of the following is used to ligate large blood vessels ?
A:-Aneurism clip
B:-Foley's catheter
C:-Splint
D:-Umbilical tape
Ans: D
44:-Theophylline is a non-competitive inhibitor of
A:-Phosphodiesterase
B:-Peroxidase
C:-Aldehyde dehydrogenase
D:-Carbonic anhydrase
Ans: A
45:-Intracellular enzyme which is a combination of heme and protein and act as catalyst in biological oxidation are termed as
A:-Hemoglobin
B:-Cytochromes
C:-Creatine kinase
D:-Transferrin
Ans: B
46:-Aminophylline is a stable mixture of theophylline with which of the following ?
A:-Aminocaproic acid
B:-Amiloride
C:-Ethyl oleate
D:-Ethylene diamine
Ans: D
47:-The pharmacokinetic parameter that describes the efficiency of elimination of drug from the body is
A:-Half life
B:-Clearance
C:-Excretion
D:-Metabolism
Ans: B
48:-Drug containing saponin glycoside as major constituent
A:-Cascara
B:-Ginko
C:-Brahmi
D:-Quassia
Ans: C
49:-Which of the following is an additive drug combination ?
A:-Amlodipine + Atenolol
B:-Histamine + Adrenaline
C:-Sulphamethoxazole + Trimethoprime
D:-Tyramine + MAO inhibitors
Ans: A
50:-5-HT antagonist used to control chemotherapy induced nausea and vomiting
A:-Risperidone
B:-Ondansetrone
C:-Cyproheptadine
D:-Clozapine
Ans: B
51:-Cardioselective beta blocker
A:-Propranolol
B:-Timolol
C:-Carvedilol
D:-Metoprolol
Ans: D
52:-Synthetic Cannabinoid
A:-Methadone
B:-Tramadol
C:-Naloxone
D:-Nabilone
Ans: D
53:-Most abundant cation in the extra cellular fluid
A:-Potassium
B:-Calcium
C:-Sodium
D:-Chloride
Ans: C
54:-The Medicinal and Toilet Preparations Act came in to force in
A:-1957
B:-1967
C:-1958
D:-1968
Ans: A
55:-Class I B antiarrhythmic drug
A:-Disopyramide
B:-Amiodarone
C:-Lidocaine
D:-Verapamil
Ans: C
56:-Causative organism of Plague
A:-Arbovirus
B:-Rat flea
C:-Clostridium tetani
D:-Yersinia pestis
Ans: D
57:-All enzymes involved in glycolysis are present in
A:-Mitochondria
B:-Blood
C:-Cytosol
D:-Cellwall
Ans: C
58:-The normal range of serum potassium level
A:-96-106 mEq/L
B:-1.5-2.2 mEq/L
C:-136-145 mEq/L
D:-3.5-5.0 mEq/L
Ans: D
59:-Water purified by distillation or reverse osmosis and meets the specifications for purity as per IP which is free from pyrogens and not intended to be sterile is
A:-Purified water
B:-Sterile water for injection
C:-Deionized water
D:-Water for injection
Ans: D
60:-The desirable level of total serum cholesterol in adults
A:-Less than 200 mg/dL
B:-Less than 240 mg/dL
C:-More than 200 mg/dL
D:-More than 240 mg/dL
Ans: A
61:-Which of the following is mainly used as a diuretic ?
A:-Ginseng
B:-Mustard
C:-Ginko
D:-Gokhru
Ans: D
62:-Tissue amine widely distributed in plants animals and in the venom of bees and wasps
A:-Serotonine
B:-Tyramine
C:-Histamine
D:-Adrenaline
Ans: C
63:-An indication of renal function which is used to estimate glomerular filtration rate is
A:-Serum urea
B:-Serum alkaline phosphatase
C:-Blood urea nitrogen
D:-Serum creatinine
Ans: D
64:-Inadequate blood flow to a part of the body secondary to constriction or blockage of the supplying artery
A:-Infarction
B:-Ischemia
C:-Necrosis
D:-Eclampsia
Ans: B
65:-Which among the following is an analytical agency constituted for efficient administration of D&C Act
A:-Central Drugs Laboratory
B:-Controlling Authority
C:-DTAB
D:-Drugs Consultative Committee
Ans: A
66:-A toxoid vaccine is
A:-Detoxicated endotoxin
B:-Detoxicated cellular fraction
C:-Detoxicated exotoxin
D:-Antitoxin
Ans: C
67:-The difference that exists between the intake and output of nitrogen both being expressed in terms of grams N per day is
A:-Blood Urea Nitrogen
B:-Non-Nitrogen Protein
C:-Protein Nitrogen
D:-Nitrogen balance
Ans: D
68:-Which of the following is a book of secondary entry ?
A:-Cash book
B:-Two column cash book
C:-Ledger
D:-Journal
Ans: C
69:-The ability of sulphides in highly alkaline pH to reduce the disulphide linkage in the aminoacid cysteine is the principle behind
A:-Sulphur candles
B:-Sulphite preservatives
C:-Sulphide depilatories
D:-Sulphate antidotes
Ans: C
70:-Which of the following is deficient in Vitamin D ?
A:-Cod liver oil
B:-Halibut oil
C:-Eggs
D:-Shark liver oil
Ans: D
71:-Which of the following monoclonal antibody is fully human origin ?
A:-Daclizumab
B:-Infliximab
C:-Adalimumab
D:-Edrecolomab
Ans: C
72:-The assets and liabilities of a business organization is
A:-Profit and loss account
B:-Balance Sheet
C:-Trial balance
D:-Debentures
Ans: B
73:-Centrally acting cough suppressant
A:-Ambroxolol
B:-Codeine
C:-Bromhexine
D:-Ammonium bicarbonate
Ans: B
74:-Which of the following is preferred for dressing wounds infected with pyogenic bacteria ?
A:-Magsulf
B:-Eusol
C:-AF lotion
D:-Mercurochrome solution
Ans: B
75:-The quantity of sodium chloride required to prepare 400 ml of 0.9% solution
A:-2.6 gm
B:-3.25 gm
C:-3.6 gm
D:-2.25 gm
Ans: C
76:-Aminoacid present in high concentration in brain tissues
A:-Glutamic acid
B:-Lysine
C:-Arginine
D:-Proline
Ans: A
77:-Locally applied protein precipitants with low cell permeability are known as
A:-Epilatories
B:-Astringents
C:-Humactants
D:-Keratolytics
Ans: B
78:-Metal cylinders filled with nitrous oxide for hospital use is painted in
A:-Blue
B:-Grey
C:-White
D:-Black
Ans: A
79:-Which of the following is not a legal requirement for opening a drug store ?
A:-Location
B:-Minimum space
C:-Drug licence
D:-Store arrangements
Ans: A
80:-Lanolin is also known as
A:-Carnauba wax
B:-Anhydrous wool fat
C:-Hydrous wool fat
D:-Spermaceti
Ans: C