TRANSFUSION MEDICINE (BLOODBANK)- PAGE 1
TRANSFUSION MEDICINE (BLOODBANK) MCQs
1. All are true about collection bag except
(A) Easy to transport [B] Need more storage space (C) Component separation easy (D) No chance for breakage
Ans: B
2. Which among the following is the best source of safe blood?
(A) Voluntary non-remunerated donor (B) Replacement donors (C) Professional donor (D) Directed donor
Ans: A
3. The storage temperature of blood for platelet concentrate is
(A) 4-10°C (B) 1-6°C (C) 18-20°C(D) 20-24°C
Ans: D
4. Antibodies present on the surface of RBC is tested by
(A) Direct Coombs test in serum (B) indirect Coombs test in RBC
(C) Direct Coombs test in RBC [D) indirect Coombs test in serum
Ans: C
5. Post transfusion survival of red cells in CPDA anticoagulated blood is:
(A) 20 days [B] 25 days (C) 30 days (D) 35 days
Ans: D
6. Changes that occur in stored blood include all except
(A) Decrease in platelet count (B) Decrease in granulocytes (C) Decrease in RBC count (D) Decrease in pH
Ans: C
7. Leucodepleted blood product means
(A) Removal of 50% of leucocytes with loss of less than 5% or red cells
(B) Removal of 70% of leucocytes with loss of less than 20% of red cells
(C)Removal of 60% of leucocytes with loss of less than 10% of red cells
(D) Removal of 80% of leucocytes with loss of less than 30% of red cells
Ans: B
8. Advantage of buffy coat platelets compared to PEP platelets include all except
(A) Minimal cell contamination (B) Rich in leucocytes (C) Better platelet Survival (D) High yield of plasma
Ans: B
9. Indication for packed red cell transfusion
[A] Leukemia (B) Aplastic anemia
[C] Hemophilia (D) Shock
Ans: B
10. What is fresh frozen plasma?
(A) Plasma separated from blood, frozen within 6 hours at -20 deg C
(B) Plasma separated from blood, frozen within 2 hours at -10 deg C
(C) Plasma separated from blood, frozen within 12 hours at -20 deg C
(D) Plasma separated from blood frozen within 6 hours at -10 deg C
Ans: A
11. Cryoprecipitate may be indicated for treatment of all except
(A) Hemophilia (FE) Thrombocytopenia
(C) Von Willebrand disease (D) Fibrinogen deficiency
Ans: B
12. Indication for transfusion of irradiated blood components are all except
(A) Patients with severe Thrombocytopenia
(B) Patients with leukemia
[C] Patients with bone marrow transplant
[D) Patients with extensive chemotherapy
Ans: A
13. Advantage of blood complement therapy
(A) Reduces transfusion related diseases
[B) Reduces all transfusion reactions
(C) Reduces volume overload
(D) Reduces Cost
Ans: C
14. Age of an ideal donor should be between
(A) 18-45 yrs
(B) 18-65 yrs
[C) 20—45 yrs
[D] 20—55 yrs
Ans: B
15. Precautions to be taken while collecting blood include all except
(A) Venepuncture should be clean
(B) Blood flow should be rapid and uninterrupted
(C] Bag should never be agitated
(D) Appropriate volume of blood should be collected
Ans: C
16. Volume of anticoagulant preservative solution in collection bag
[A) 14 ml of CPDA for preserving 100 ml of blood
[B) 20 ml of CPDA for preserving 100 mi of blood
[C) 14 ml of CPDA for preserving 350 ml of blood
(D) 20 ml of CPDA for preserving 350 ml of blood
Ans: A
17. The advantage of adding additives to blooe beg Include
(A) Prevents bacterial growth
(B) Increases the viscocity of blood
(C) Extends the storage of red blood cells
(D) Decreases the leukocyte survival
Ans: C
18. Storage of blood in frozen state is done by adding
(A) Adenine (B) Citrate
(C) Glycerol (D) Dextrose
Ans: C
19. Refractoriness to Platelet transfusion is due to
(A) Decreased platelet production (B) Production of allo-antibodies
(C) Defective platelet function (D) Defective cross matching
Ans: B
20:-______________ substance is present in hydatid cyst fluid.
A:-`Le^b`
B:-`Tj^a`
C:-`P^k`
D:-`Le^x`
Ans: C
21:-Author of the book titled "Experiments on the transfusion of blood by syringe"
A:-William Harvey
B:-James Blundell
C:-Baxton-Hick
D:-Richard Lower
Ans: B
22:-First blood bank in India was established at
A:-Delhi
B:-Calcutta
C:-Pune
D:-Bombay
Ans: B
23:-AIDS cases are reported first in the year
A:-1960
B:-1971
C:-1981
D:-1980
Ans: C
24:-World's first hospital blood bank at cook county hospital, Chicago was began by
A:-James Blundell
B:-Fantus
C:-Mollison
D:-Ottenberg
Ans: B
25:-Professional Blood donation banned in India since
A:-January 1, 1999
B:-January 1, 1997
C:-January 1, 1998
D:-January 1, 1996
Ans: C
26:-Government of India made test for Human Immunodeficiency Virus (HIV) mandatory by notifying in drugs and cosmetic act on _________.
A:-1991
B:-1985
C:-1989
D:-1990
Ans: C
27:-License of Blood storage centre is valid for
A:-3 years
B:-2 years
C:-5 years
D:-1 year
Ans: B
28:-National voluntary blood donation day October 1st is in memory of
A:-Dr. J.G. Jolly
B:-Karl Landsteiner
C:-William Harvey
D:-Wiener Klinische
Ans: A
29:-Govt. of India published the National Blood policy in the year
A:-2002
B:-2000
C:-1999
D:-2001
Ans: A
30:-Cycle of disaster management include
A:-Preparedness
B:-Response
C:-Recovery
D:-All of the above
Ans: D
31:- Quality indicator mandated for accredited blood banks to monitor and report every 6 months
A:-Donor deferral rate
B:-Donor reaction rate
C:-Percentage of components prepared
D:-Wastage rate
Ans: D
32:-Frozen RBC can be stored up to
A:-10 years
B:-25 years
C:-5 years
D:-One year
Ans: A
33:-Biochemical composition of RBC membrane is
A:-52% protein, 40% lipid and 8% carbohydrate
B:-40% protein, 52% lipid and 8% carbohydrate
C:-52% carbohydrate, 40% lipid and 8% protein
D:-None of the above
Ans: A
34:-Minimum hemoglobin value required to accept an adult as a blood donor is
A:-12 gm/dl
B:-12.5 gm/dl
C:-13 gm/dl
D:-11.5 gm/dl
Ans: B
35:-Expiry date of irradiated platelet is
A:-1 day
B:-3 days
C:-7 days
D:-No change from original expiration date
Ans: D
36:-ABO gene locus is in chromosome
A:-9q34.2
B:-19p13.3
C:-6p24.2
D:-4q28-q31
Ans: A
37:-Latest included blood group is ISBT is
A:-LAN
B:-VEL
C:-AUG
D:-FORS
Ans: C
38:-Compatible IV solution that can be administered through the same transfusion gel is _________.
A:-Ringer lactate
B:-20% dextrose
C:-Plasmalyte A
D:-10% dextrose
Ans: C
39:-Which of the following antibodies is most likely to be naturally occurring
A:-Anti K
B:-Anti M
C:-Anti e
D:-Anti `JK^a`
Ans: B
40:-Of the following a non carbohydrate antigen is
A:-H
B:-Lewis
C:-I
D:-Rh
Ans: D
41:-A null phenotype of RBCs resistant/delayed lysis by 2 m urea
A:-Fy (a-b-)
B:-Le (a-b-)
C:-JK (a-b-)
D:-Co (a-b-)
Ans: C
42:-Half life of Hydroxy Ethyl Starch (HES)
A:-6 hrs
B:-12 hrs
C:-24 hrs
D:-48 hrs
Ans: C
43:-Super transfusion protocol in thalassemic children recommended hemoglobin target as
A:-8-9 gm/dl
B:-9-10 gm/dl
C:-11-12 gm/dl
D:-12-13 gm/dl
Ans: C
44:-Focus of oxygen sensor in foetus is
A:-Kidney
B:-Liver
C:-Carotid sinus
D:-Spleen
Ans: B
45:-Approximately at ___________ age children attain the adult value of PT, aPTT and INR
A:-6 years
B:-10 years
C:-8 years
D:-16 years
Ans: D
46:-False statement about CD44 glycoprotein
A:-Present on most of the tissues
B:-Minor component of RBC membrane
C:-Involved in T and B cell activation
D:-Involved in WBC adhesion activities
Ans: B
47:-One transfusion set can be used for multiple transfusions up to
A:-6 hrs
B:-4 hrs
C:-12 hrs
D:-24 hrs
Ans: B
48:-Best filter to transfuse leuco reduced and irradiated single donor plasma is
A:-Standard blood filter
B:-Macroaggregate filter
C:-Leuco reduction filter
D:-Irradiation filter
Ans: A
49:-Anticoagulant commonly used in Apheresis procedure
A:-CPD
B:-ACD
C:-CPDA
D:-EDTA
Ans: B
50:-This reagent is not used to enhance antigen antibody reaction
A:-DTT
B:-Polybrene
C:-PEG
D:-Ficin
Ans: A
(A) Easy to transport [B] Need more storage space (C) Component separation easy (D) No chance for breakage
Ans: B
2. Which among the following is the best source of safe blood?
(A) Voluntary non-remunerated donor (B) Replacement donors (C) Professional donor (D) Directed donor
Ans: A
3. The storage temperature of blood for platelet concentrate is
(A) 4-10°C (B) 1-6°C (C) 18-20°C(D) 20-24°C
Ans: D
4. Antibodies present on the surface of RBC is tested by
(A) Direct Coombs test in serum (B) indirect Coombs test in RBC
(C) Direct Coombs test in RBC [D) indirect Coombs test in serum
Ans: C
5. Post transfusion survival of red cells in CPDA anticoagulated blood is:
(A) 20 days [B] 25 days (C) 30 days (D) 35 days
Ans: D
6. Changes that occur in stored blood include all except
(A) Decrease in platelet count (B) Decrease in granulocytes (C) Decrease in RBC count (D) Decrease in pH
Ans: C
7. Leucodepleted blood product means
(A) Removal of 50% of leucocytes with loss of less than 5% or red cells
(B) Removal of 70% of leucocytes with loss of less than 20% of red cells
(C)Removal of 60% of leucocytes with loss of less than 10% of red cells
(D) Removal of 80% of leucocytes with loss of less than 30% of red cells
Ans: B
8. Advantage of buffy coat platelets compared to PEP platelets include all except
(A) Minimal cell contamination (B) Rich in leucocytes (C) Better platelet Survival (D) High yield of plasma
Ans: B
9. Indication for packed red cell transfusion
[A] Leukemia (B) Aplastic anemia
[C] Hemophilia (D) Shock
Ans: B
10. What is fresh frozen plasma?
(A) Plasma separated from blood, frozen within 6 hours at -20 deg C
(B) Plasma separated from blood, frozen within 2 hours at -10 deg C
(C) Plasma separated from blood, frozen within 12 hours at -20 deg C
(D) Plasma separated from blood frozen within 6 hours at -10 deg C
Ans: A
11. Cryoprecipitate may be indicated for treatment of all except
(A) Hemophilia (FE) Thrombocytopenia
(C) Von Willebrand disease (D) Fibrinogen deficiency
Ans: B
12. Indication for transfusion of irradiated blood components are all except
(A) Patients with severe Thrombocytopenia
(B) Patients with leukemia
[C] Patients with bone marrow transplant
[D) Patients with extensive chemotherapy
Ans: A
13. Advantage of blood complement therapy
(A) Reduces transfusion related diseases
[B) Reduces all transfusion reactions
(C) Reduces volume overload
(D) Reduces Cost
Ans: C
14. Age of an ideal donor should be between
(A) 18-45 yrs
(B) 18-65 yrs
[C) 20—45 yrs
[D] 20—55 yrs
Ans: B
15. Precautions to be taken while collecting blood include all except
(A) Venepuncture should be clean
(B) Blood flow should be rapid and uninterrupted
(C] Bag should never be agitated
(D) Appropriate volume of blood should be collected
Ans: C
16. Volume of anticoagulant preservative solution in collection bag
[A) 14 ml of CPDA for preserving 100 ml of blood
[B) 20 ml of CPDA for preserving 100 mi of blood
[C) 14 ml of CPDA for preserving 350 ml of blood
(D) 20 ml of CPDA for preserving 350 ml of blood
Ans: A
17. The advantage of adding additives to blooe beg Include
(A) Prevents bacterial growth
(B) Increases the viscocity of blood
(C) Extends the storage of red blood cells
(D) Decreases the leukocyte survival
Ans: C
18. Storage of blood in frozen state is done by adding
(A) Adenine (B) Citrate
(C) Glycerol (D) Dextrose
Ans: C
19. Refractoriness to Platelet transfusion is due to
(A) Decreased platelet production (B) Production of allo-antibodies
(C) Defective platelet function (D) Defective cross matching
Ans: B
20:-______________ substance is present in hydatid cyst fluid.
A:-`Le^b`
B:-`Tj^a`
C:-`P^k`
D:-`Le^x`
Ans: C
21:-Author of the book titled "Experiments on the transfusion of blood by syringe"
A:-William Harvey
B:-James Blundell
C:-Baxton-Hick
D:-Richard Lower
Ans: B
22:-First blood bank in India was established at
A:-Delhi
B:-Calcutta
C:-Pune
D:-Bombay
Ans: B
23:-AIDS cases are reported first in the year
A:-1960
B:-1971
C:-1981
D:-1980
Ans: C
24:-World's first hospital blood bank at cook county hospital, Chicago was began by
A:-James Blundell
B:-Fantus
C:-Mollison
D:-Ottenberg
Ans: B
25:-Professional Blood donation banned in India since
A:-January 1, 1999
B:-January 1, 1997
C:-January 1, 1998
D:-January 1, 1996
Ans: C
26:-Government of India made test for Human Immunodeficiency Virus (HIV) mandatory by notifying in drugs and cosmetic act on _________.
A:-1991
B:-1985
C:-1989
D:-1990
Ans: C
27:-License of Blood storage centre is valid for
A:-3 years
B:-2 years
C:-5 years
D:-1 year
Ans: B
28:-National voluntary blood donation day October 1st is in memory of
A:-Dr. J.G. Jolly
B:-Karl Landsteiner
C:-William Harvey
D:-Wiener Klinische
Ans: A
29:-Govt. of India published the National Blood policy in the year
A:-2002
B:-2000
C:-1999
D:-2001
Ans: A
30:-Cycle of disaster management include
A:-Preparedness
B:-Response
C:-Recovery
D:-All of the above
Ans: D
31:- Quality indicator mandated for accredited blood banks to monitor and report every 6 months
A:-Donor deferral rate
B:-Donor reaction rate
C:-Percentage of components prepared
D:-Wastage rate
Ans: D
32:-Frozen RBC can be stored up to
A:-10 years
B:-25 years
C:-5 years
D:-One year
Ans: A
33:-Biochemical composition of RBC membrane is
A:-52% protein, 40% lipid and 8% carbohydrate
B:-40% protein, 52% lipid and 8% carbohydrate
C:-52% carbohydrate, 40% lipid and 8% protein
D:-None of the above
Ans: A
34:-Minimum hemoglobin value required to accept an adult as a blood donor is
A:-12 gm/dl
B:-12.5 gm/dl
C:-13 gm/dl
D:-11.5 gm/dl
Ans: B
35:-Expiry date of irradiated platelet is
A:-1 day
B:-3 days
C:-7 days
D:-No change from original expiration date
Ans: D
36:-ABO gene locus is in chromosome
A:-9q34.2
B:-19p13.3
C:-6p24.2
D:-4q28-q31
Ans: A
37:-Latest included blood group is ISBT is
A:-LAN
B:-VEL
C:-AUG
D:-FORS
Ans: C
38:-Compatible IV solution that can be administered through the same transfusion gel is _________.
A:-Ringer lactate
B:-20% dextrose
C:-Plasmalyte A
D:-10% dextrose
Ans: C
39:-Which of the following antibodies is most likely to be naturally occurring
A:-Anti K
B:-Anti M
C:-Anti e
D:-Anti `JK^a`
Ans: B
40:-Of the following a non carbohydrate antigen is
A:-H
B:-Lewis
C:-I
D:-Rh
Ans: D
41:-A null phenotype of RBCs resistant/delayed lysis by 2 m urea
A:-Fy (a-b-)
B:-Le (a-b-)
C:-JK (a-b-)
D:-Co (a-b-)
Ans: C
42:-Half life of Hydroxy Ethyl Starch (HES)
A:-6 hrs
B:-12 hrs
C:-24 hrs
D:-48 hrs
Ans: C
43:-Super transfusion protocol in thalassemic children recommended hemoglobin target as
A:-8-9 gm/dl
B:-9-10 gm/dl
C:-11-12 gm/dl
D:-12-13 gm/dl
Ans: C
44:-Focus of oxygen sensor in foetus is
A:-Kidney
B:-Liver
C:-Carotid sinus
D:-Spleen
Ans: B
45:-Approximately at ___________ age children attain the adult value of PT, aPTT and INR
A:-6 years
B:-10 years
C:-8 years
D:-16 years
Ans: D
46:-False statement about CD44 glycoprotein
A:-Present on most of the tissues
B:-Minor component of RBC membrane
C:-Involved in T and B cell activation
D:-Involved in WBC adhesion activities
Ans: B
47:-One transfusion set can be used for multiple transfusions up to
A:-6 hrs
B:-4 hrs
C:-12 hrs
D:-24 hrs
Ans: B
48:-Best filter to transfuse leuco reduced and irradiated single donor plasma is
A:-Standard blood filter
B:-Macroaggregate filter
C:-Leuco reduction filter
D:-Irradiation filter
Ans: A
49:-Anticoagulant commonly used in Apheresis procedure
A:-CPD
B:-ACD
C:-CPDA
D:-EDTA
Ans: B
50:-This reagent is not used to enhance antigen antibody reaction
A:-DTT
B:-Polybrene
C:-PEG
D:-Ficin
Ans: A
51:-Refrigerated whole blood reduces the transmissions of
A:-Hepatitis A
B:-Hepatitis B
C:-Hepatitis C
D:-Syphilis
Ans: D
52:-Blood group antigen that is not enlisted in the routine antibody identification panel is
A:-M
B:-I
C:-`Le^a`
D:-`JK^a`
Ans: B
53:-In large volume neonatal transfusions nephrotoxicity is due to the metabolite
A:-Sodium metaphosphate
B:-Adenosine dioxamine
C:-1, 4-dioxy chloroquine
D:-2, 8-dioxy adenine
Ans: D
54:- Recommended temperature for storage of cryopreserved umbilical cord blood cells
A:- ≤-150°C
B:- ≤-210°C
C:- ≤100°C
D:-≤-80°C
Ans: A
55:-Albumen treatment is not indicated in
A:-Burns
B:-Shock
C:-Cachexia
D:-Plasmapheresis
Ans: C
56:-Transplantation of porcine heart valve to a man is an example of
A:-Syngenic transplant
B:-Xenogenic transplant
C:-Allogenic transplant
D:-Autologous transplant
Ans: B
57:- Tests for QC of peripheral blood stem cells include
A:-Clonogenic assay
B:-Cell viability
C:-Sterility testing
D:-All of the above
Ans: D
58:-Granulocyte components to be transfused within _____________ hrs after collection.
A:-8 hrs
B:-24 hrs
C:-48 hrs
D:-6 hrs
Ans: B
59:-An ideal blood substitute have the following characteristic except
A:-Increased availability
B:-Long shelf life
C:-Universal compatibility
D:-Infectious chance as blood products
Ans: D
60:-Blood warmer use is not indicated in
A:-Neonatal exchange transfusion
B:-Patients with cold aggulutinins
C:-Rapid transfusion through central venous catheter
D:-Rapid transfusion in children
Ans: C
61:-"Leap frog" technique relate to the context of
A:-Apheresis plasma collection
B:-Autologous transfusion
C:-Irradiation of blood products
D:-Pathogen inactivation of blood products
Ans: B
62:-Hyper coagulable state is associated with all except
A:-Antithromobin deficiency
B:-Increased protein S
C:-Factor V Leiden mutation
D:-F XII deficiency
Ans: B
63:-Post haematopoietic stem cell transplant prophylaxis is given to combat
A:-Herpes simplex virus
B:-Cytomegalovirus
C:-Epstein Barr virus
D:-All of the above
Ans: D
64:-During preparative regimen in a bidirectional incompatible bone marrow transplant following blood group plasma can only be transfused
A:-AB blood group
B:-Donor blood group
C:-Recipient blood group
D:-O blood group
Ans: A
65:-Hematological malignancy associated with autoimmune hemolytic anemia is
A:-Acute Lymphoblastic leukemia
B:-Chronic myeloid leukemia
C:-(1) and (2)
D:-Chronic lymphocytic leukemia
Ans: D
66:-Blood group system related to McLeod syndrome is
A:-Kell
B:-Kidd
C:-Duffy
D:-Lewis
Ans: A
67:-Strategies for augmenting cell dose in umbilical cord stem cell transplantation include all except
A:-Exvivo expansion of umbilical cord blood stem and progenitor cells
B:-Intra bone marrow injection
C:-Thyroid hormone treatment
D:-Multiple unit umbilical cord blood transplantation
Ans: C
68:-Percentage of red cell suspension used in column agglutination technique is
A:-1%
B:-5%
C:-10%
D:-40%
Ans: A
69:-'Witebsky' test is used for
A:-Irregular antibody detection
B:-Secretory status
C:-Compatibility test
D:-Transfusion reactions
Ans: B
70:-Elution method good for eluting IgG antibody
A:-Heat elution
B:-Glycine EDTA elution
C:-Both (1) and (2)
D:-None of the above
Ans: B
71:-Auto antibody specificity in PCH patients is
A:-I
B:-i
C:-P
D:-`p^k`
Ans: C
72:-Source of Erythropoeitin
A:-Renal interstitial fibroblasts
B:-Renal tubular epithelial cells
C:-Peri sinusoidal cells in liver
D:-All of the above
Ans: D
73:-Antibody in renal patients undergoing dialysis with formaldehyde sterilized machine
A:-Anti M
B:-Anti N
C:-Anti P
D:-Anti S
Ans: B
74:-A positive direct coombs test can be due to
A:-Auto antibodies to intrinsic red cell antigen
B:-Allo antibody against transfused red cell antigen
C:-Drug induced antibodies
D:-All of the above
Ans: D
75:-Sulf hydryl reagents are all except
A:-DAT
B:-DTT
C:-2 ME
D:-AET
Ans: A
76:-Colour of the label used for autologous transfusions units
A:-Pink
B:-Orange
C:-Green
D:-Blue
Ans: C
77:-A donor experiences facial muscle twitch during platelet pheresis, what should be done?
A:-Detach ACD line
B:-Decrease return rate
C:-Add saline to the line
D:-Stop the procedure
Ans: B
78:-All are clinical features of iron overload
A:-Heart failure
B:-Diabetes
C:-Hyperthyroidism
D:-Liver failure
Ans: C
79:-Which of the following blood group gene is located in chromosome I?
A:-Kell
B:-Kidd
C:-Duffy
D:-Lutheran
Ans: C
80:-Maximum age for a first time blood donor
A:-50 yrs
B:-60 yrs
C:-40 yrs
D:-45 yrs
Ans: B
81:-Patient with body surface area of `2 m^2` is transfused with 4 × 10" platelet, initial platelet count of 5000/μl and post transfusion count 25000/μl. What would be the corrected count increment?
A:-5000/μl
B:-10,000/μl
C:-20,000/μl
D:-8000/μl
Ans: B
82:-Most important antibody causing TRALI?
A:-HNA-3a
B:-HNA-2a
C:-HNA-1a
D:-None of the above
Ans: A
83:-Routine premedication to transfusion recipient is
A:-Advised
B:-Not advised
C:-Optional
D:-None of the above
Ans: B
84:-Lethal triad of massive transfusion
A:-Anemia, coagulopathy and hypothermia
B:-Coagulopathy, hypothermia, acidosis
C:-Hypothermia, acidosis, anemia
D:-Anemia, coagulopathy, acidosis
Ans: B
85:-Massive transfusion with stored citrated blood cause
A:-Left shift of `O_2` dissociation curve
B:-Right shift of `O_2` dissociation curve
C:-Increase 2, 3 DPG
D:-None of the above
Ans: A
86:-Not used as an adjacent in transfusion therapy for trauma and burns patient
A:-ε amino caproic acid
B:-Tranexamic acid
C:-Methyl cellulose
D:-None of the above
Ans: C
A:-Hepatitis A
B:-Hepatitis B
C:-Hepatitis C
D:-Syphilis
Ans: D
52:-Blood group antigen that is not enlisted in the routine antibody identification panel is
A:-M
B:-I
C:-`Le^a`
D:-`JK^a`
Ans: B
53:-In large volume neonatal transfusions nephrotoxicity is due to the metabolite
A:-Sodium metaphosphate
B:-Adenosine dioxamine
C:-1, 4-dioxy chloroquine
D:-2, 8-dioxy adenine
Ans: D
54:- Recommended temperature for storage of cryopreserved umbilical cord blood cells
A:- ≤-150°C
B:- ≤-210°C
C:- ≤100°C
D:-≤-80°C
Ans: A
55:-Albumen treatment is not indicated in
A:-Burns
B:-Shock
C:-Cachexia
D:-Plasmapheresis
Ans: C
56:-Transplantation of porcine heart valve to a man is an example of
A:-Syngenic transplant
B:-Xenogenic transplant
C:-Allogenic transplant
D:-Autologous transplant
Ans: B
57:- Tests for QC of peripheral blood stem cells include
A:-Clonogenic assay
B:-Cell viability
C:-Sterility testing
D:-All of the above
Ans: D
58:-Granulocyte components to be transfused within _____________ hrs after collection.
A:-8 hrs
B:-24 hrs
C:-48 hrs
D:-6 hrs
Ans: B
59:-An ideal blood substitute have the following characteristic except
A:-Increased availability
B:-Long shelf life
C:-Universal compatibility
D:-Infectious chance as blood products
Ans: D
60:-Blood warmer use is not indicated in
A:-Neonatal exchange transfusion
B:-Patients with cold aggulutinins
C:-Rapid transfusion through central venous catheter
D:-Rapid transfusion in children
Ans: C
61:-"Leap frog" technique relate to the context of
A:-Apheresis plasma collection
B:-Autologous transfusion
C:-Irradiation of blood products
D:-Pathogen inactivation of blood products
Ans: B
62:-Hyper coagulable state is associated with all except
A:-Antithromobin deficiency
B:-Increased protein S
C:-Factor V Leiden mutation
D:-F XII deficiency
Ans: B
63:-Post haematopoietic stem cell transplant prophylaxis is given to combat
A:-Herpes simplex virus
B:-Cytomegalovirus
C:-Epstein Barr virus
D:-All of the above
Ans: D
64:-During preparative regimen in a bidirectional incompatible bone marrow transplant following blood group plasma can only be transfused
A:-AB blood group
B:-Donor blood group
C:-Recipient blood group
D:-O blood group
Ans: A
65:-Hematological malignancy associated with autoimmune hemolytic anemia is
A:-Acute Lymphoblastic leukemia
B:-Chronic myeloid leukemia
C:-(1) and (2)
D:-Chronic lymphocytic leukemia
Ans: D
66:-Blood group system related to McLeod syndrome is
A:-Kell
B:-Kidd
C:-Duffy
D:-Lewis
Ans: A
67:-Strategies for augmenting cell dose in umbilical cord stem cell transplantation include all except
A:-Exvivo expansion of umbilical cord blood stem and progenitor cells
B:-Intra bone marrow injection
C:-Thyroid hormone treatment
D:-Multiple unit umbilical cord blood transplantation
Ans: C
68:-Percentage of red cell suspension used in column agglutination technique is
A:-1%
B:-5%
C:-10%
D:-40%
Ans: A
69:-'Witebsky' test is used for
A:-Irregular antibody detection
B:-Secretory status
C:-Compatibility test
D:-Transfusion reactions
Ans: B
70:-Elution method good for eluting IgG antibody
A:-Heat elution
B:-Glycine EDTA elution
C:-Both (1) and (2)
D:-None of the above
Ans: B
71:-Auto antibody specificity in PCH patients is
A:-I
B:-i
C:-P
D:-`p^k`
Ans: C
72:-Source of Erythropoeitin
A:-Renal interstitial fibroblasts
B:-Renal tubular epithelial cells
C:-Peri sinusoidal cells in liver
D:-All of the above
Ans: D
73:-Antibody in renal patients undergoing dialysis with formaldehyde sterilized machine
A:-Anti M
B:-Anti N
C:-Anti P
D:-Anti S
Ans: B
74:-A positive direct coombs test can be due to
A:-Auto antibodies to intrinsic red cell antigen
B:-Allo antibody against transfused red cell antigen
C:-Drug induced antibodies
D:-All of the above
Ans: D
75:-Sulf hydryl reagents are all except
A:-DAT
B:-DTT
C:-2 ME
D:-AET
Ans: A
76:-Colour of the label used for autologous transfusions units
A:-Pink
B:-Orange
C:-Green
D:-Blue
Ans: C
77:-A donor experiences facial muscle twitch during platelet pheresis, what should be done?
A:-Detach ACD line
B:-Decrease return rate
C:-Add saline to the line
D:-Stop the procedure
Ans: B
78:-All are clinical features of iron overload
A:-Heart failure
B:-Diabetes
C:-Hyperthyroidism
D:-Liver failure
Ans: C
79:-Which of the following blood group gene is located in chromosome I?
A:-Kell
B:-Kidd
C:-Duffy
D:-Lutheran
Ans: C
80:-Maximum age for a first time blood donor
A:-50 yrs
B:-60 yrs
C:-40 yrs
D:-45 yrs
Ans: B
81:-Patient with body surface area of `2 m^2` is transfused with 4 × 10" platelet, initial platelet count of 5000/μl and post transfusion count 25000/μl. What would be the corrected count increment?
A:-5000/μl
B:-10,000/μl
C:-20,000/μl
D:-8000/μl
Ans: B
82:-Most important antibody causing TRALI?
A:-HNA-3a
B:-HNA-2a
C:-HNA-1a
D:-None of the above
Ans: A
83:-Routine premedication to transfusion recipient is
A:-Advised
B:-Not advised
C:-Optional
D:-None of the above
Ans: B
84:-Lethal triad of massive transfusion
A:-Anemia, coagulopathy and hypothermia
B:-Coagulopathy, hypothermia, acidosis
C:-Hypothermia, acidosis, anemia
D:-Anemia, coagulopathy, acidosis
Ans: B
85:-Massive transfusion with stored citrated blood cause
A:-Left shift of `O_2` dissociation curve
B:-Right shift of `O_2` dissociation curve
C:-Increase 2, 3 DPG
D:-None of the above
Ans: A
86:-Not used as an adjacent in transfusion therapy for trauma and burns patient
A:-ε amino caproic acid
B:-Tranexamic acid
C:-Methyl cellulose
D:-None of the above
Ans: C
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